Clinical and cost effectiveness of Curcuma longa mouthwash versus Listerine® mouthwash in controlling halitosis among a group of Egyptian children: A randomized clinical trial | ||
| Ain Shams Dental Journal | ||
| Volume 38, Issue 2, June 2025, Pages 402-409 PDF (1.24 M) | ||
| Document Type: Original articles | ||
| DOI: 10.21608/asdj.2025.356473.1828 | ||
| Authors | ||
| Eman M. Elsaeed* 1; Eman Elmasry2; Passant Nagi3 | ||
| 1Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University, Cairo, Egypt | ||
| 2Professor of Pediatric Dentistry and Dental Public Health, Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University, Giza, Egypt | ||
| 3Assistant Professor of Pediatric Dentistry and Dental Public Health, Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University, Giza, Egypt | ||
| Abstract | ||
| Aim: Due to the many adverse effects of certain synthetic medications as well as the evolution of bacterial resistance, the present study aimed to compare the clinical and cost-effectiveness of mouthwash containing Curcuma longa (Turmeric extract) to Listerine® mouthwash and placebo mouthwash in reducing halitosis in a group of Egyptian youngsters. Materials and Methods: The study was a randomized clinical trial with a three-arm, parallel-group, and blinded allocation. Thirty healthy children aged 8-12 were recruited, subjected to full-mouth clinical rehabilitation before allocation, and divided into groups A, B, and C, assigned for turmeric mouthwash, Listerine, and Placebo, respectively. All participants were instructed to use the given mouthwash with 10 ml twice daily for two weeks, stop using it for two weeks, and then re-use it for two weeks. Halitosis score was recorded using Tanita HC-312F device after 2, 4, and 6 weeks of using mouthwashes. Cost-effectiveness was recorded, and halitosis-positive and negative subjects; clinical parameters were compared using the Chi-square test at P <0.05. Results: Regarding halitosis scores, there was a significant difference between the tested groups at recruitment and after 2 and 6 weeks. All groups' clinical effectiveness revealed that groups A and B were 100% effective. Group B had the highest average cost, followed by groups A and C. Conclusion: It was concluded that turmeric mouthwash was equally clinically effective and more cost-effective than Listerine® mouthwash. | ||
| Keywords | ||
| Halitosis; Essential oil mouthwash; Listerine®; Curcuma longa; Turmeric mouthwash | ||
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