Assessment of the toxicity of nano-kaolinite on colorectal cancer cells | ||
| Advances in Basic and Applied Sciences | ||
| Article 2, Volume 6, Issue 1, October 2025, Pages 13-17 PDF (1.31 M) | ||
| Document Type: Commentaries | ||
| DOI: 10.21608/abas.2025.417940.1080 | ||
| Authors | ||
| Eman A Hussien* 1; Mohamed M Omran2; Mahmoud E Awad3; Mohga S Abdalla4 | ||
| 1Biotechnology program, Chemistry Department, Faculty of Science, Helwan University, 11795, Cairo, Egypt. | ||
| 2Biochemistry sector, Chemistry Department, Faculty of Science, Helwan University, 11795, Cairo, Egypt. | ||
| 3Applied Mineralogy lab, Department of Geology, Faculty of Science, Al-Azhar University, Nasr City 11884, Cairo, Egypt | ||
| 4Biochemistry sector, Chemistry Department, Faculty Of Science, Helwan University , Cairo, Egypt. | ||
| Abstract | ||
| One of the leading causes of death worldwide is cancer, particularly colorectal cancer, which ranks third among cancer-related deaths according to recent studies. In light of this reality, the importance of finding a treatment that avoids the pitfalls of previous treatments increases. These treatments may be beneficial in treating colorectal cancer, but they also harm the entire body. Thanks to the promising idea of using nanotechnology to develop an efficient treatment, there are many options to work on. Despite its rocky nature, kaolin possesses properties that could transform treatments if exploited optimally. Many researches illustrated the promising role of kaolinite in many medical applications. This research aims to obtain pure kaolinite in nano scale form, to make sure of the validity of kaolinite itself chemically using Fourier Transform Infrared (FTIR) and analysis technique X-ray Fluorescence Spectroscopy (XRF), then, to test its potential toxicity in eliminating colorectal cancer cells using cell viability assay (MTT). | ||
| Keywords | ||
| Colorectal cancer; Nanokaolinite; Caco2 cell line | ||
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