Effect of Low-Level Laser Therapy on Patients with Burning Mouth Syndrome Secondary to Type 2 Diabetes Mellitus | ||
| Alexandria Dental Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 06 October 2025 PDF (852.94 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/adjalexu.2025.367903.1613 | ||
| Authors | ||
| Nermien Elhammamy* 1; Azza Mohamed Zaki2; Hanan Abdelaziz3 | ||
| 1Oral Medicine and Diagnosis, Faculty of Dentistry, Alexandria University, Alexandria, Egypt | ||
| 2Oral Medicine, Periodontology, Diagnosis and Radiology, Faculty of Dentistry, Alexandria University, Alexandria , Egypt. | ||
| 3Medical Biochemistry dep. Faculty of Medicine, Alexandria University, Alexandria, Egypt | ||
| Abstract | ||
| Background: Burning mouth syndrome (BMS) may arise secondary to type 2 diabetes mellitus (DM). Other than proper glycemic control, no other modality is universally effective in management of the symptoms. Low-level laser therapy has shown a favorable outcome in many studies dealing with burning mouth syndrome. As such, it can be used to treat BMS secondary to DM. Objective: Assessing the effect of low-level laser therapy on burning mouth syndrome secondary to type 2 diabetes mellitus versus sham treatment. Materials and Methods: This study was conducted on controlled diabetic patients with BMS. Group A received low-level laser therapy using a diode laser (980nm, 1W, continuous wave mode), while group B received a sham laser treatment. Both groups were assessed at baseline, 4 weeks (end of treatment), and 12 weeks (2-month follow-up) regarding VAS and quality of life (QoL) using OHIP-14 questionnaires. Results: Intergroup comparison of VAS showed great significance after 4 weeks of treatment (p=0.045) in favor of the laser group. As for QoL, intergroup comparison showed a significant result after 4 weeks (p<0.001) and 12 weeks (p=0.025). Conclusion: The 980 nm diode laser was effective in reducing pain scores after 4 weeks of treatment and improving QoL after 4 and 12 weeks. This is most likely attributed to its potent analgesic effects, though they appear to be temporary. As such, it’s a great tool for the alleviating symptoms of BMS secondary to DM. | ||
| Keywords | ||
| Burning Mouth Syndrome; Low-level laser therapy; LLLT; photobiomodulation; diabetes mellitus | ||
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