Comprehensive Clinical Insights into the Diagnosis, Management, and Interprofessional Approaches to Deep Neck Infections for Healthcare Professionals | ||
| Egyptian Journal of Chemistry | ||
| Volume 68, Issue 13, December 2025, Pages 1301-1311 PDF (1.05 M) | ||
| Document Type: Review Articles | ||
| DOI: 10.21608/ejchem.2025.400755.12004 | ||
| Authors | ||
| Ghadah Mousa Naseeb* 1; Mona Awadh Alanazi2; Fatimah Tuwaileh Almasoudi2; Najla Awadh Sattam Alanazi2; Amirah Oudah Alanazi2; Zaina Zaki Almohammed2; Fatmah Ali Khrami2; Bader Majed Alotaibi2; Ilham Muhammad Albalawi2; Ramzi Hasan Al Hamad2 | ||
| 1 Ministry of National Guard, Saudi Arabia | ||
| 2Ministry of National Guard, Saudi Arabia | ||
| Abstract | ||
| Background: Deep neck infections (DNIs) are serious suppurative processes within the fascial planes of the neck, often originating from odontogenic or oropharyngeal sources. They pose a significant risk due to their potential for rapid progression, airway compromise, and life-threatening complications like mediastinitis and sepsis. Aim: This article provides a comprehensive clinical overview of DNIs for healthcare professionals, covering etiology, epidemiology, pathophysiology, diagnostic evaluation, and evidence-based management strategies to improve patient outcomes. Methods: The review synthesizes current medical knowledge, highlighting that DNIs are typically polymicrobial, involving oral flora such as streptococci, staphylococci, and anaerobes. Diagnosis relies on a high clinical suspicion based on history and physical exam, confirmed primarily with contrast-enhanced computed tomography (CECT) to localize abscesses and define anatomical extent. Laboratory markers like elevated neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP) aid in severity assessment. Results: Management is multidisciplinary. The cornerstone treatment involves prompt administration of broad-spectrum intravenous antibiotics and timely surgical or image-guided drainage of established abscesses. Securing the airway is the paramount initial priority in cases of potential compromise. Conclusion: DNIs represent a medical emergency requiring swift diagnosis and aggressive management. A coordinated interprofessional approach is essential for successful outcomes, emphasizing early imaging, appropriate antimicrobial therapy, source control, and vigilant airway management to prevent morbidity and mortality. | ||
| Keywords | ||
| Deep Neck Infection; Retropharyngeal Abscess; Parapharyngeal Abscess; Airway Compromise; Contrast-Enhanced CT; Surgical Drainage | ||
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