Successful Pregnancy Outcome in a Couple with Long-Standing Infertility Overcoming Severe Male Factor Azoospermia, Polycystic Ovarian Syndrome, and Intrahepatic Cholestasis of Pregnancy | ||
| Aswan Africa Obstetrics and Gynecology Journal | ||
| Volume 1, Issue 3, September 2025, Pages 145-153 PDF (1.47 M) | ||
| Document Type: Case Reports | ||
| DOI: 10.21608/aaogj.2025.430793.1029 | ||
| Authors | ||
| Hanan Jawad* 1; Nawfal Mansoor2 | ||
| 1Specialist of Obstetrics & Gynecology. Arbil - Iraq | ||
| 2Dr. Nawfal Mansoor, Ataia Al-Emaraty hospital, Erbil/Eraq | ||
| Abstract | ||
| This report describes the successful management of a couple with 15 years of primary infertility due to severe male factor azoospermia and female polycystic ovarian syndrome (PCOS). Following surgical sperm retrieval and in vitro fertilization (IVF), the patient conceived on the first attempt. The pregnancy was complicated by severe intrahepatic cholestasis of pregnancy (ICP) at 22 weeks, with markedly elevated liver enzymes and bile acids. Despite the indication for termination at this gestational age, multidisciplinary management with close maternal–fetal monitoring enabled continuation of pregnancy until 34 weeks, when an elective cesarean section resulted in the delivery of a healthy female infant. Both mother and baby were discharged in good condition. This case highlights the value of collaborative reproductive and hepatological management in optimizing outcomes in complex infertility and pregnancy scenarios. | ||
| Keywords | ||
| Azoospermia; PCOS; Intrahepatic cholestasis of pregnancy; Testicular sperm extraction; IVF | ||
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