Bioactive Potential of Rumex pictus: Phytochemical Constituents, Antioxidant, and Antimicrobial Properties | ||
| Mansoura Journal of Biology | ||
| Volume 72, Issue 4, December 2025, Pages 1-8 PDF (873.07 K) | ||
| Document Type: Research Article | ||
| DOI: 10.21608/mjb.2025.420982.1008 | ||
| Authors | ||
| Alaa T. Elghazy1; Ashraf A. El-Said1; Yasser El-Amier* 2 | ||
| 1Botany Department, Faculty of Science, Mansoura University, Mansoura - 35516, Egypt | ||
| 2Botany Department, Faculty of Science, Mansoura University, Mansoura, Egypt | ||
| Abstract | ||
| Rumex pictus Forssk., a species traditionally used in North African and Middle Eastern medicine, has remained largely unexplored in terms of its phytochemical and biological properties. The present study was designed to investigate the phytochemical composition, antioxidant activity, and antimicrobial potential of the methanolic extract obtained from the aerial parts of this plant. Phytochemical screening revealed the presence of a wide spectrum of bioactive secondary metabolites, with flavonoids, phenols, glycosides, and anthraquinones occurring in high concentrations, while tannins and steroids were detected at moderate levels. The antioxidant activity, assessed using the DPPH radical scavenging assay, demonstrated a clear dose-dependent response, with an IC₅₀ value of 29.77 mg/mL. Although this reflects moderate antioxidant potential, the activity is consistent with the substantial levels of phenolic and flavonoid compounds identified, which are known to contribute significantly to free radical scavenging and oxidative stress mitigation. Antimicrobial evaluation, carried out through the agar well diffusion method, confirmed that the methanolic extract possesses broad-spectrum antibacterial effects. The extract inhibited the growth of both Gram-positive and Gram-negative bacteria, including S. aureus, Bacillus cereus, Escherichia coli, and S. typhi. While the inhibitory effects were weaker than those of standard antibiotics, the extract displayed pronounced activity against Gram-positive strains, particularly S. aureus and B. cereus. These findings demonstrate that R. pictus is a valuable reservoir of bioactive compounds with relevant antioxidant and antimicrobial properties. | ||
| Keywords | ||
| Rumex pictus; Desert; DPPH, pathogenic bacteria, phytochemical | ||
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