Exploring the link between schizophrenia and periodontal disease: a systematic review | ||
Benha Medical Journal | ||
Volume 42, Issue 10, October 2025, Pages 115-123 PDF (591.09 K) | ||
Document Type: Review Article | ||
DOI: 10.21608/bmfj.2025.402139.2527 | ||
Authors | ||
Jaswitha vintha* 1; Gangolu Meghana2; Ramanarayana Boyapati3; Ravindranath Dhulipalla4; LAKSHMI KANTH K KOLAPARTHY5 | ||
1Takellapadu | ||
2assistant professor, sibar dental college, takkellapadu, guntur. | ||
3Dr.Boyapati Ramanarayana, BDS, MDS. Professor, Department of Periodontology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India. | ||
4Sibar institute of dental sciences | ||
5Department of Periodontology Sibar institute of dental sciences India | ||
Abstract | ||
Schizophrenia is a chronic psychiatric disorder often associated with compromised self-care and health outcomes. Emerging evidence suggests a link between schizophrenia and poor oral health, particularly periodontal disease. This systematic review aims to evaluate the association between schizophrenia and periodontal health by analyzing clinical outcomes in affected individuals. A comprehensive electronic search was conducted across MEDLINE, PubMed, Scopus, and EMBASE databases using relevant MeSH terms. The search focused on studies published within the last 15 years. Inclusion criteria targeted randomized clinical trials assessing periodontal health in patients diagnosed with schizophrenia. After screening and applying predefined inclusion and exclusion criteria, seven eligible studies were selected. Data extraction was performed using a standardized grid to ensure consistency. The analysis of the selected studies revealed that individuals with schizophrenia consistently exhibit poorer periodontal health compared to the general population. Key contributing factors include medication-induced xerostomia, neglect of oral hygiene, cognitive impairment, and behavioral challenges. Common periodontal parameters such as plaque index, gingival bleeding, and probing depth were significantly worse in the schizophrenia group across studies. This review highlights a clear association between schizophrenia and increased risk of periodontal disease. The findings underscore the importance of integrating dental care into the overall health management of individuals with schizophrenia. Routine periodontal assessments, tailored oral hygiene education, and interdisciplinary collaboration are essential for improving oral health outcomes in this vulnerable population. | ||
Keywords | ||
Schizophrenia; Periodontal disease; Oral health; Systematic review; Psychiatric disorders | ||
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