Right Ventricular Strain and Short-Term Prognosis in Patients with First Acute Anterior STEMI without Evidence of RV Infarction | ||
Benha Medical Journal | ||
Articles in Press, Accepted Manuscript, Available Online from 16 October 2025 PDF (912.45 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/bmfj.2025.413801.2615 | ||
Authors | ||
Hany Hassan Ebaid1; Mahmoud A. Abdallah* 2; Ahmed A. Mohammed3; Karim H Elakabawi4 | ||
1Assistant Professor of Cardiovascular Medicine Faculty of Medicine - Benha University | ||
2(Faculty of Medicine, Benha University) | ||
3Professor of Cardiovascular Medicine Faculty of Medicine - Benha University | ||
4Department of cardiovacular medicine, Banha UniversiLecturer of Cardiovascular Medicine Faculty of Medicine - Benha UniversityWith the submission of this manuscript, we confirm that ty | ||
Abstract | ||
This prospective observational single-center study at Benha University Hospital (Sept 2023–Aug 2024) included 200 consecutive patients with first acute anterior STEMI without right ventricular (RV) infarction. Patients were divided into “complicated” and “non-complicated” groups based on the occurrence of major adverse cardiovascular events (MACE). All underwent clinical examination, ECG, echocardiography, and speckle tracking echocardiography. The mean age was 62 ± 7 years; 59% were male. Comorbidities included diabetes (51%), hypertension (59%), dyslipidemia (33%), and smoking (43%). Compared to the non-complicated group, the MACE group had higher RVMPI (0.50 ± 0.03 vs 0.44 ± 0.05, p<0.001) and lower TAPSE (15.24 ± 1.13 mm vs 17.18 ± 0.49 mm, p<0.001) and FAC (34.7 ± 1.6% vs 39.2 ± 1.4%, p<0.001). Right ventricular free wall strain (19.1 ± 2.2% vs 20.5 ± 0.6%) and RV global longitudinal strain (RVGLS) (16.1 ± 2.1% vs 17.4 ± 0.3%) were also significantly reduced in the MACE group (p<0.001). Ejection fraction was slightly higher in the MACE group (40 ± 4% vs 38 ± 4%, p<0.001). The study concludes that in first anterior STEMI patients without RV infarction, reduced RVGLS and RV free wall strain are critical prognostic markers, independently associated with higher risk of MACE, including heart failure and mortality, highlighting the prognostic value of RV strain assessment. | ||
Keywords | ||
Right Ventricular Strain; First Acute Anterior STEMI; RV Infarction; Prognosis; Echocardiography | ||
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