Instillation of Lidocaine Intraperitoneally Improves Postoperative Analgesia at Cesarean Delivery | ||
| Benha Medical Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 16 October 2025 PDF (572.96 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bmfj.2025.407741.2583 | ||
| Authors | ||
| Ibrahim I. Swidan1; Ali A. Bendary2; Labiba K. Elsayed3; Aliaa A. Ali* 4 | ||
| 1Professor of Obstetrics and Gynecology, Faculty of Medicine, Benha University | ||
| 2Assistant Professor of Obstetrics and Gynecology, Faculty of Medicine, Benha University | ||
| 3Lecturer of Obstetrics and Gynecology, Faculty of Medicine, Benha University | ||
| 4Assistant Lecturer of Anatomy and Embryology, Faculty of Medicine, Benha University | ||
| Abstract | ||
| Background: Cesarean delivery has become the most frequently performed surgical procedure in many countries, with its prevalence rising in recent decades. Effective management of postoperative pain is essential for patient recovery. This study aimed to evaluate the efficacy and safety of intraperitoneal lidocaine for postoperative analgesia following cesarean delivery. Methods: In this prospective, double-blinded, placebo-controlled clinical trial, 221 patients undergoing cesarean delivery—either primigravida or with a previous cesarean section and no extensive adhesions—were enrolled. Patients were randomly assigned into two equal groups using a computer-generated table. At the end of surgery, just before parietal peritoneum or fascia closure, Group A (lidocaine group) received 20 mL of 2% lidocaine with epinephrine (1:200,000) intraperitoneally, while Group B (placebo group) received 20 mL of normal saline. Results: Group A reported significantly lower postoperative pain scores at 4, 6, 12, and 24 hours (P < 0.001) based on the visual analogue scale (VAS). Additionally, patients in the lidocaine group required less supplemental analgesia and experienced fewer instances of moderate to severe pain. Conclusion: Intraperitoneal lidocaine significantly improves postoperative analgesia in cesarean delivery without increasing adverse effects. It is a safe, simple, and cost-effective adjunct for pain management in this surgical setting. | ||
| Keywords | ||
| Lidocaine; Cesarean Delivery; Intraperitoneally; Postoperative Analgesia | ||
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