Evaluation of Endoscopic Repair of Cerebrospinal Fluid (CSF) Rhinorrhea with Single Layer Graft versus Multilayers Graft | ||
| SVU-International Journal of Medical Sciences | ||
| Volume 8, Issue 2, July 2025, Pages 631-644 PDF (613.04 K) | ||
| Document Type: Original research articles | ||
| DOI: 10.21608/svuijm.2025.366183.2140 | ||
| Authors | ||
| Ahmed Mamdouh AbdelAziz* 1; Ahmed Ali Ibrahim2; Zaki F Aref1; Aida A. Abdelmaksoud1 | ||
| 1Department of Otorhinolaryngology, Faculty of Medicine, South Valley University, Qena, Egypt. | ||
| 2Department of Otorhinolaryngology, Faculty of Medicine, Alexandria University, Alexandria , Egypt. | ||
| Abstract | ||
| Background: Endoscopic repair of skull base defect is the treatment of choice in cases of CSF rhinorrhea. Objectives: To evaluate the results of endoscopic repair with single-layer grafting versus multi-layer grafting in cases of CSF rhinorrhea. Patients and methods : This study included 50 patients with CSF rhinorrhea. They are divided into two groups. Group A included 25 patients who underwent repair of the defect using a single-layer graft. Group B included 25 patients who underwent repair by multi-layer graft. Postoperative follow-up of all cases for one year. Results: This study included 50 patients: 34 were females (68%) and 16 were males (32%) with the mean age of 39.9 ± 12.03 . Group A included 25 patients. The mean age 39.9 ± 12.95 in comparison to 39.8 ± 11.69 years in Group B showed no significant difference. Group A included 72% females and 28% males compared to 64% females and 36% males in Group B with no significant difference. As regards etiology, the most common cause in Group A is neoplastic, but the most common cause in Group B is spontaneous causes. The comparison between group (A) and group (B) regarding defect data showed no significant differences. Comparison between the two studied groups regarding grafts and flaps showed a highly significant difference was observed between the group (A) and group (B) in the use of autologous fat grafts, fascia Lata grafts, Naso-septal flap, bone grafts, and free mucosal grafts. Comparison between group (A) and group (B) regarding postoperative outcomes revealed no significant differences in all parameters. Conclusion: Both techniques showed similar outcomes, with no significant differences in complications or CSF leak recurrence. | ||
| Keywords | ||
| Cerebrospinal fluid (CSF) rhinorrhea; Endoscopic; Single layer graft multilayer graft; Spontaneous leak | ||
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