Modification, Characterization and Biological Effectiveness of Anti-flu Drug | ||
البحوث التطبيقية في العلوم والانسانيات | ||
Volume 2, Issue 1, 2025, Pages 156-175 PDF (901.58 K) | ||
Document Type: المقالة الأصلية | ||
DOI: 10.21608/aash.2025.459901 | ||
Authors | ||
Afaf M. Jamal; Ahd M. Salah; Ola W. Ahmed; Sandra N. Muftah; Shams T. Abdul Hakam; Shrouk Y. Abdo; Shrouq R. Ahmed; Osama F. Mohamed | ||
Associate Professor in Organic chemistry Ain Shams University, Faculty of Education, bachelor’s degree of Science and Education (Preparatory and Secondary), Chemistry | ||
Abstract | ||
In recent decades, current flu treatments faced major challenges. Accordingly, there is a huge need for improved access, new drugs, and faster care. It explores promising options like natural compounds and advanced antivirals. Enhancing vaccines and case tracking are key to fighting future flu outbreaks. Moreover, highlighting Amantadine’s role as an antiviral and Parkinson’s treatment, noting resistance issues and side effects. It also outlines improved, eco-friendly synthesis methods for safer and more efficient production. The condensation of Amantadine with 3-formylchromone, forming the targeted Schiff base, which shows spectroscopic agreement and computational promise against H5N1, supporting further lab testing as a potential treatment for resistant strains | ||
Keywords | ||
Antiviral Drugs; Anti-flu drugs; Amantadine; Molecular docking | ||
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