Comparative toxicity of some pesticides to common carp and their effects on biochemical targets in living tissues | ||
Journal of Pest Control and Environmental Sciences | ||
Volume 2, Issue 1, 1990, Pages 29-41 PDF (692.12 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/jpces.1990.460591 | ||
Authors | ||
K. S. El-Gendy* ; N. M. Aly; N. S. Ahmed; A. H. El-Sebae | ||
Plant Protection Department, Faculty of Agriculture, Alexandria University, Alexandria, Egypt. | ||
Abstract | ||
Four pesticides were evaluated in laboratory studies to determine acute toxicity (96-hr ) to common carp (Cyprinus carpio L). LC50 values of pyrazophos, glyphosate, fenvalerate, and copper sulfate were 6.11, 5.89,3.98 x 10-3 and 11.75 mg/1 respectively. The activity of acetyl cholinesterase (AChE), acid phosphatase (APase), glutathione S-transferase (GST) and transaminases (glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) were measured in brain, liver, kidney, gill, and muscle in a comparative study. An in-vivo effects of half LC50 and LC50, levels of tested compounds on different enzymes in different organs were studied. Pyrazophos and glyphosate caused the highest inhibition of brain AChE. Liver and kidney APases were stimulated by the tested compounds. GST was inhibited in the brain and gill, while it was stimulated in liver of treated fish. All tested compounds caused spontaneous activation of liver GOT and muscle GPT, while caused significant inhibition of brain GOT. | ||
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