Biological Activity of an Endophytic Fungus Phomopsis sojae Ay05 isolated from Glycine L. max | ||
Mansoura Journal of Biology | ||
Volume 48, Issue 3, September 2020, Pages 13-19 PDF (826.26 K) | ||
Document Type: Research Article | ||
DOI: 10.21608/mjb.2020.460687 | ||
Authors | ||
Ayman Ali* ; Ahmed Gebreil; Ashraf Elsayed | ||
Botany Department, Faculty of Science, Mansoura University, 35516 Mansoura City, Egypt. | ||
Abstract | ||
In the present study, the endophytic fungal isolate of Phomopsis sojae associated with Glycine L. max was investigated and identified according to its cultural and morphological characteristics, in addition to 18srRNAsequencing and phylogenetic analysis. The biological activity of ethyl acetate, aqueous and methanol extracts of fungal growth, i.e. antimicrobial, antioxidant and antitumor was evaluated. The potentiality of fungal extracts against some of G+ and G- bacteria such as Staphlococcus ,Bacillus, Klebsiella and also Candida has been investigated. In other words, the antioxidant potentiality of aqueous extract was superior to other ones, being 0.25351 µg/ml. Interestingly, the ethyl acetate of fungal extracts showed a moderate activity against tumor cell line of breast cancer with IC50=22.9 µg/ml. Ultimately, these a aforementioned results indicated the role of some microorganisms in production of new bioactive compounds, with feasibility and could be eco-friendly. | ||
Keywords | ||
Endophytic fungus; antioxidant; Phomopsis sojae; Glycine L. max; antitumor | ||
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