Effect of the organophosphate, cyanophos on some biochemical parameters in the liver and brain of the male albino mouse Mus muscules | ||
Journal of Pest Control and Environmental Sciences | ||
Volume 5, Issue 1, June 1993, Pages 1-15 PDF (1.82 M) | ||
Document Type: Original Article | ||
DOI: 10.21608/jpces.1993.460802 | ||
Authors | ||
Mohamed F. F. Bayomy* 1; Amal A. Eisa2 | ||
1Zoology Dept., Fac., of Science, Menoufia Univ. | ||
2Plant Protection Dept., Faculty of Agric. Menoufia Univ. | ||
Abstract | ||
The effect of the sub lethal dose (1/4 LD 50 value) o the organophosphate, cyanophos was studied in the tissues of liver and brain of male albino m use, Mus muscules. The results cleared that: 1- In the treated mice with either a single dose or repeated one, of tested sub lethal dose, there is an exhibited significant decrease in the total hepatic rote in compared with the control. The decline as observed in al l time points of the experiment. 2- The activity of the liver enzymes Glutamate Oxaloacetate Transaminase and Glutamate Pyruvate Transaminase (GOT, GPT) and alkaline phosphatase was noticed to be decreased. 3- Little decrease in the amount of brain protein content was observed with no significant difference co pared with the control at all time intervals in case of both the single and repeated dose. 4- The treatment has led to a significant decrease in t e activity of brain enzymes (GOT, GPT and acetylcholine esterase) at 24 hr after intoxication and there after till 192 hrs. | ||
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