Prevalence of osteoporosis and its associated work-related factors and obesity among a sample of Egyptian women indoor workers and employees | ||
| Journal of the Arab Society for Medical Research | ||
| Volume 16, Issue 2, July 2021, Pages 106-114 PDF (122.13 K) | ||
| DOI: 10.4103/jasmr.jasmr_17_21 | ||
| Abstract | ||
| Background/aim Obesity and osteoporosis are progressive diseases with complex etiology. They constitute a major public health concern nowadays. This study aimed to assess the prevalence of osteoporosis, vitamin D profile, and its relation to obesity, bone markers, and leptin among a sample of Egyptian women indoor workers and employees at the National Research Centre. Patients and methods A cross-sectional study that included 116 Egyptian women aged 25–60 years. Anthropometric measurements (body weight, height, and BMI), dual-energy radiograph absorptiometry [bone mineral density (BMD) and its score at both lumbar spines and neck of the femur], and laboratory investigations (leptin, calcium, vitamin D, and C-terminal peptide) were done for all participants. They were classified according to their BMI and BMD- scores at lumbar spines and femur neck. Results Osteoporosis was diagnosed among 11.2, 25.2, and 6.8% of participants using the BMD- score at lumbar spines, femur neck, and at the two sites respectively; osteopenia was diagnosed among 44.8, 51.3, and 25%, respectively. Osteoporosis was significantly more frequent among normal weight women than overweight/obese ones. Normal weight osteoporotic women had significantly higher values of vitamin D and C-terminal peptide, and lower values of leptin and BMI than the nonosteoporotic ones. Among osteoporotic women, BMI had a significant negative correlation with vitamin D. BMI had significant positive correlations with BMD at both lumbar spines and femur neck and their scores among nonosteoporotic women and total sample. BMI had a significant positive correlation with the C-terminal peptide among the osteoporotic, nonosteoporotic, and total sample, with leptin and age among the osteoporotic and total sample. Conclusion BMI had a significant positive correlation with hypovitaminosis D, C-terminal peptide, leptin, and age. It had a significant positive correlation with BMD among nonosteoporotic women, but not among osteoporotic ones. Obesity protects from osteoporosis. Dual-energy radiograph absorptiometry at lumbar spines underestimate the diagnosis of osteoporosis and osteopenia. | ||
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