Chronic lung sepsis in a sample of Egyptian patients with type II diabetes mellitus | ||
| Journal of the Arab Society for Medical Research | ||
| Volume 16, Issue 2, July 2021, Pages 115-121 PDF (1.58 M) | ||
| DOI: 10.4103/jasmr.jasmr_25_21 | ||
| Abstract | ||
| Background/aim Chronic lung sepsis is one of the major causes of chronic respiratory symptoms such as chronic cough and pus formation. It has received very little attention over recent decades. In addition, failure of its characterization in immunocompromised patients such as diabetics has led to under-recognition and lack of early management. Patients and methods In this study, 61 patients with symptoms and signs of chronic lung disease were enrolled from Ahmed Maher Teaching Hospital in Egypt. Of them, 32 fulfilling the criteria of chronic lung sepsis were classified into two groups: diabetic (17 patients) and nondiabetic (15 patients). All of the patients were subjected to detailed medical history, thorough clinical examination, laboratory investigations, sputum culture and sensitivity, and high-resolution computed tomography of the chest. Results A total of 23 cases were diagnosed as bronchiectasis, four cases were diagnosed as lung abscess, two cases were pyopneumothorax, whereas there was one case each of infected cyst, empyema, and infected emphysematous bullous. Sputum culture showed that gram-negative organisms were more evident in the diabetic group. The management of cases of chronic lung sepsis showed the use of double or triple antimicrobial therapy in the diabetic group. Conclusion Targeting good control of pneumonia in patients with type II diabetes mellitus using double or triple antimicrobial therapy is essential to inhibit the progression of pulmonary infections to chronic lung sepsis. | ||
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