Effect of Dietary Management in Patients with Chronic Kidney Disease | ||
| Egyptian Journal of Health Care | ||
| Volume 16, Issue 4, December 2025, Pages 114-120 PDF (462.26 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhc.2025.461201 | ||
| Authors | ||
| Ruaa Nashat Al-Saffar1; Frqad Salih Jawad1; Amasee Falah Jabbar1; Ahmed Neamah Abed1; Ahmed Ali Shaaban1; Mahmoud M. Al-Mukhtar2; Rania Abd Elmohsen Abo El Nour3 | ||
| 1Anaesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq. | ||
| 2Anaesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq. &College of Medicine, Al-Mustaqbal University, 51001 Babylon, Iraq. | ||
| 3Anaesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq. & Community Health Nursing Department, Beni-Suef Health Technical Institute, Ministry of Health, Beni-Suef 62511, Egypt. | ||
| Abstract | ||
| Objective: This research explores the relationship between diet and kidney disease, controlled study was to examine the sedoanalgesia effects of ketamine-dexmedetomidine and ketamine-midazolam during dressing changes in burn patients. Methods: a total of 90 adult burn patients classified as ASA physical statuses I and II were enrolled in the study. The patients were randomly assigned to one of three groups. A continuous infusion of dexmedetomidine was administered to the dexmedetomidine group (group KD) (n = 30) at a rate of 1 μg kg-1, ten minutes prior to the dressing change, while the midazolam group (group KM) (n = 30) received midazolam at a rate of 0.05 mg kg-1, and the saline group (group KS) (n = 30) received a continuous intravenous infusion of saline. One minute before the dressing change, each participant was given 1 mg kg-1 of ketamine intravenously. Data on hemodynamic variables, pain and sedation scores, the number of patients needing additional ketamine, the duration of the dressing change, and recovery time were recorded. Results: Systolic blood pressure (SBP) levels were notably lower at baseline and post-ketamine administration, as well as 5, 10, and 15 minutes after the procedure in the KD group compared to the other groups (P <0.05). There were no significant differences in pain scores among the groups throughout the duration of the study. Sedation scores at the end of the first hour were significantly higher in the KD group compared to the KM and KS groups (P <0.05). Conclusions: In burn patients receiving dressing changes, both combinations of ketamine with dexmedetomidine and ketamine with midazolam provided effective sedation and pain relief without significant adverse effects. | ||
| Keywords | ||
| Dexmedetomidine; Ketamine and Midazolam | ||
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