A Study of the Impact of Anemia on Morbidity and Mortality in Children with Dilated Cardiomyopathy | ||
| Journal of Current Medical Research and Practice | ||
| Volume 10, Issue 4, October 2025, Pages 105-110 PDF (563.76 K) | ||
| Document Type: Original Article | ||
| Authors | ||
| Mohammed Ammar* ; Osama Mahmoud El-Asheer; Nagwa Ali Mohammed | ||
| Pediatrics Department, Faculty of Medicine, Assiut University, Assiut, Egypt. | ||
| Abstract | ||
| Introduction: A history, physical examination, and noninvasive tests are used to make the clinical diagnosis of dilated cardiomyopathy (DCM), which is a heart muscle disease marked by systolic dysfunction and dilatation of the left or both ventricles. Aim: To determine the influence of anemia on morbidity and mortality in children with DCM, with or without heart failure, and its correlation with the clinical and echocardiographic findings. Patient and Methods: This was a longitudinal prospective study to assess the impact of anemia on children and adolescents known to have dilated cardiomyopathy attending Asyut University Hospital. Cardiomyopathic patients were divided into two groups (anemic and non-anemic), and both groups underwent clinical and echocardiographic evaluation at the beginning and after a minimum of four months. All infants, children, and adolescents with dilated cardiomyopathy who were diagnosed clinically and by echocardiography were included. Results: Symptoms and signs of heart failure were observed more often among anemic patients. On follow-up of the cardiomyopathic anemic group after 4 months of treatment of anemia, we found that with increased hemoglobin level, there is a significant improvement in symptoms and signs of heart failure, and a significant increase in left ventricular systolic function (FS %) detected by echocardiography. Conclusion: Treatment of anemia in patients with cardiomyopathy resulted in a significant increase in left ventricular systolic function (FS %) detected by echocardiography and improved manifestations of heart failure. | ||
| Keywords | ||
| Anemia; Echocardiography; Cardiomyopathy | ||
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