Comparative study on the effect of oral administration of some insecticides on serum glucose, some lipids, and non- protein nitrogen constituents of rabbit | ||
| Journal of Pest Control and Environmental Sciences | ||
| Volume 6, Issue 2, December 1998, Pages 37-54 PDF (1.03 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jpces.1998.461517 | ||
| Author | ||
| Maged Yassin* | ||
| Dept. of Faculty of Science Islamic Univ. GAZA, PALESTINE. | ||
| Abstract | ||
| The present study was conducted to investigate and compare the intoxication effects of daily oral administration of 1/10 LD50/kg body wt. of Tamaron, Parathion and Confider for 10 days on serum non-protein nitrogen constituents e.g. urea, uric acid and creatinine, glucose, cholesterol and triglycerides of rabbit. The daily oral administration of any of the tree insecticides for 10 days caused a general increase of urea concentration in rabbits blood serum compared to the control level. In general, significant increase of urea content was observed from the third day of inoculation Insecticides administration also raised up the concentration of uric acid and the highest serum content of uric acid was noticed in the tenth day of insecticides treatment. However, creatinine content did not show any significant changes in response to the treatments by Tamaron, Parathion or Confider during all the time intervals studied. Glucose content of rabbits blood serum showed different fluctuations a response to insecticides administration. On the other hand, Parathion and Confider, in general, showed significant increase in serum cholesterol content at the different time intervals studied whereas Tamaron produced significant increase in serum cholesterol level at the fifth day of inoculation. Triglycerides content of rabbits blood serum ended differently to the treatments by the tested insecticides. It is possible to conclude that insecticides administration for 10 days, even a low doses i.e. 10 LD50/kg body wt., had harmful effects on kidney, liver, carbohydrate and lipid metabolisms. | ||
| Keywords | ||
| Tamaron; Parathion; Confider; serum non-protein nitrogen constituents – urea-uric acid creatinine-glucose- cholesterol-triglycerides in blood serum of rabbis | ||
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