Gingival Crevicular Fluid and Placental Tissue Levels of Interleukin-17 as a Possible Marker for Preterm Labor in Patients with Chronic Periodontitis
Gamal, A., Agoor, M., Shaker, O., El-Demerdash, F., Sweed, M. (2017). Gingival Crevicular Fluid and Placental Tissue Levels of Interleukin-17 as a Possible Marker for Preterm Labor in Patients with Chronic Periodontitis. EKB Journal Management System, 1(1), 1-11. doi: 10.26810/2017.a1
Ahmed Y. Gamal; Mohamed Agoor; Olfat G. Shaker; Fatma H. El-Demerdash; Mohamed Samir Sweed. "Gingival Crevicular Fluid and Placental Tissue Levels of Interleukin-17 as a Possible Marker for Preterm Labor in Patients with Chronic Periodontitis". EKB Journal Management System, 1, 1, 2017, 1-11. doi: 10.26810/2017.a1
Gamal, A., Agoor, M., Shaker, O., El-Demerdash, F., Sweed, M. (2017). 'Gingival Crevicular Fluid and Placental Tissue Levels of Interleukin-17 as a Possible Marker for Preterm Labor in Patients with Chronic Periodontitis', EKB Journal Management System, 1(1), pp. 1-11. doi: 10.26810/2017.a1
Gamal, A., Agoor, M., Shaker, O., El-Demerdash, F., Sweed, M. Gingival Crevicular Fluid and Placental Tissue Levels of Interleukin-17 as a Possible Marker for Preterm Labor in Patients with Chronic Periodontitis. EKB Journal Management System, 2017; 1(1): 1-11. doi: 10.26810/2017.a1

Gingival Crevicular Fluid and Placental Tissue Levels of Interleukin-17 as a Possible Marker for Preterm Labor in Patients with Chronic Periodontitis

Perio J
Volume 1, Issue 1, August 2017, Pages 1-11    PDF (370.97 K)
Document Type: Original Article
DOI: 10.26810/2017.a1
Authors
Ahmed Y. Gamal* 1; Mohamed Agoor1; Olfat G. Shaker2; Fatma H. El-Demerdash1; Mohamed Samir Sweed3
1Department of Periodontology, Faculty of Dental Medicine, Ain Shams University, Cairo, Egypt.
2Department of Medical Biochemistry, Faculty of Medicine, Cairo University, Cairo, Egypt.
3Department of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Abstract
Background: The present study was conducted to evaluate the levels of interleukin (IL) – 17 in gingival crevicular fluid (GCF) and placental tissue samples of pregnant females as a possible marker in determining whether or not an association exists between chronic periodontitis and preterm labor. Methods: This case-control study included a random sample of 40 female patients, aged 18 to 35 years, who were assigned to one of the following four groups (10 subjects each): group 1 included patients who underwent spontaneous preterm birth (PB) and were diagnosed with chronic periodontitis upon clinical examination (preterm/periodontitis); group 2 included patients who underwent spontaneous PB and who had a healthy periodontium upon clinical examination (preterm/healthy periodontium); group 3 included patients who underwent spontaneous normal term birth and were diagnosed with chronic periodontitis upon clinical examination (term/periodontitis); and group 4 included patients who underwent spontaneous normal term birth and who had a healthy periodontium upon clinical examination (term/healthy periodontium). GCF and placental tissue samples were obtained from each patient and IL-17 levels were measured using enzyme-linked immunosorbent assay (ELISA). Results: GCF levels of IL-17 were significantly higher (P=0.010) in patients with chronic periodontitis compared to those with a healthy periodontium. No significant differences were observed in IL-17 levels in placental tissue samples of all study groups. Conclusion: An association between chronic periodontitis and preterm labor could not be established based on IL-17 levels measured in the present study.
Keywords
Preterm labor; periodontal medicine; periodontitis; interleukin-17; gingival crevicular fluid
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