| Biochemical targets affected by sub-lethal doses of lindane and deltamethrin | ||
| Journal of Pest Control and Environmental Sciences | ||
| Volume 3, Issue 2, December 1991, Pages 63-76 PDF (713.48 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jpces.1991.461581 | ||
| Author | ||
| Kawther S. El-Gendy* | ||
| Department of Plant Protection, Faculty of Agriculture, University of Alexandria, Alexandria, Egypt | ||
| Abstract | ||
| The effect of daily oral administration of sub-lethal doses of lindane (5 mg/kg) and deltamethrin (2 mg/kg) for three weeks on male mice after one hour and after three weeks of last dose were studied. The treated mice showed reduction of body weight. There was also a significant increase in liver, kidney, and brain: body weight ratios after three weeks of last dose. In contrast, there was a significant decrease in spleen: body weight ratio. The tested pesticides significantly inhibited mice brain ATPases (Total—ATPase, Na+, K+-ATase and Mg 2 + -ATPase) after one hour and after three weeks of treatment, except that deltamethrin significantly inhibited Mg 2 + -ATPase. Pesticides failed to produce any significant changes in the levels of δ-aminobutyric acid (GABA) and glutamic acid. | ||
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