Protein and transaminases activities modulation by sublethal concentrations of pirimiphos-methyl in blood serum of bolti fish Orechromus niloticus | ||
| Journal of Pest Control and Environmental Sciences | ||
| Volume 7, Issue 1, April 1999, Pages 71-84 PDF (739.03 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jpces.1999.462094 | ||
| Authors | ||
| Osman A. El-Gougary* 1; Saad M. M. Ismail2; Yousry M. Ahmed2 | ||
| 1Plant Protection Ins. Agric. Res Center. Cairo | ||
| 2Plant Protection Dept. Faculty of Agric. Suez Canal University. Ismailia, Egypt | ||
| Abstract | ||
| The acute toxicity of pirimiphos-methyl on bolti fish Orechromus niloticus had been evaluated, and the 96-hr LCs, was determined (3.2 ppm). The exposure of fish to sublethal concentration of pirimiphos-mehyl was utilized to investigate the non-acute effects on the modulation of protein and transaminases in blood serum of bolt fish. The results illustrated that pirimiphos-mehyl reduced the protein level in blood serum and the process of protein reduction was correlated to the increase of tested concentration. Such decrease slowed down with the increase of exposure period to reach the normal level. With regard to the results of transaminases, glutamic - oxaloscetic- transaminase (GOT) and glutamic - pyruvic transaminase (GPT) modulation in blood serum of fish at low concentration 0.32 ppm (one tenth of 96-hr LC50) of Pirimiphos-mehyl, the activities of both enzymes were decreased in Comparison to the same enzymes in untreated fish during the first 2 days of exposure and then increased over that of control. On the contrary, at the highest concentrations 0.4, 0.8 and 1.0 of the 96-hr LC50 of pirimiphos mehyl, a stimulatory action on GPT and GOT activities was observed spontaneously during the exposure period. These results suggest that the protein that the protein levels and transaminase activities of flash blood serum could be used as biomarkers for aquatic pollution caused by insecticides. | ||
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