Biochemical effects profenofos in the New Zealand white rabbit | ||
| Journal of Pest Control and Environmental Sciences | ||
| Volume 4, Issue 1, June 1992, Pages 15-30 PDF (4.76 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jpces.1992.462131 | ||
| Authors | ||
| R. A. Habiba* 1; S. M. Ismail2 | ||
| 1Department of Food Science & Technology. | ||
| 2Department of Plant Protection. Faculty of Agriculture, Suez Canal University, Ismailia, Egypt 41522 | ||
| Abstract | ||
| The in vivo effects of drifted profenofos residues on acetylcholine esterase (AChE). transaminases (glutamic-oxaloacetic transaminase, GOT and glutamicpyruvic transaminase, GPT), and the phosphatases (Acid phosphatase, Apase and alkaline phosphatase. Alkpase) in different organs (brain, liver, heart, muscles, and kidney) of the New Zealand white rabbits exposed to one-day feeding and continuous feeding on clover contaminated with the drifted pesticide were studied. The drifted profenofos was more potent to inhibit liver AChE than brain AChE. The transaminases and phosphatases showed different level of inhibition or stimulation depending on type of and time of exposure to the investigated pesticide. The disruption of enzymes from the normal values denotes biochemical impairment and lesions tissues and cellular functions because these enzymes are involved in the detoxification processes, metabolism, and biosynthesis of energetic macromolecules for different essential functions. Therefore, it is necessary to the drifted profenofos problem into consideration and to restrict its use to nonedible crops. | ||
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