The impact of chronic hepatitis B infection on hepatic steatosis grading and liver stiffness measured by FibroScan | ||
| Microbes and Infectious Diseases | ||
| Articles in Press, Accepted Manuscript, Available Online from 26 October 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mid.2025.430656.3300 | ||
| Authors | ||
| Shimaa Moustafa Mansour* ; Madonna Magdy Fahmy; kariman Helmy Elkasrawy | ||
| Department of Tropical Medicine and Infectious Diseases, Faculty of Medicine, Tanta University, Tanta, Egypt | ||
| Abstract | ||
| Background and aim: Hepatitis B virus (HBV) and metabolic dysfunction-associated fatty liver disease (MAFLD) are two of the most common chronic liver disorders . Both capable of progressing to advanced fibrosis, cirrhosis, and ultimately hepatocellular carcinoma (HCC).The interplay between HBV infection and hepatic steatosis (HS) remains a matter of debate. So the aim of this study was to evaluate the association between hepatic steatosis and fibrosis severity in chronic HBV patients using FibroScan. Patients and methods: This cross-sectional study enrolled 100 adults (≥18 years) with confirmed chronic HBV infection. Liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) were obtained using FibroScan. Results:100 adults patients were enrolled in this study with 84 patients presented with hepatic steatosis ,23 of them were grade 1 steatosis , 36 were grade 2 staetosis and 25 were grade 3 . The males were 53 and the females were 46 with a statistically significant differences between different steatosis grades(p < 0.001) The steatosis grades increased with increasing the grades of fibrosis with p 0.010*. Conclusion: Based on the results of the current study, we can concluded that the prevalence of Hepatic steatosis is relatively increased in patients with chronic hepatitis B infection with direct relationship between the grade of fibrosis and the grade of steatosis. | ||
| Keywords | ||
| HBV; Steatosis; fibroscan; CAP; LSM | ||
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