Comparative Study Between Digital Tomosynthisis and Dynamic Contrast Enhanced MRI in Diagnosis of Malignant Breast Cancer | ||
| Al-Azhar International Medical Journal | ||
| Volume 2025, Issue 6, June 2025, Pages 153-159 PDF (557.65 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aimj.2025.446623 | ||
| Authors | ||
| Aisha Ramadan Mohamed1; Noha Abdelshafy Elsaid2; Manal Farag Khaled1; Sara Mohammad Abdel kareem Mohammad1 | ||
| 1Diagnostic and Intervention Radiology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt | ||
| 2Diagnostic and Intervention Radiology, National Cancer Institute, Cairo University, Cairo, Egypt | ||
| Abstract | ||
| Background: All throughout the globe, people are dealing with the devastating effects of breast cancer (BC). It ranks first among female cancers in both industrialized and underdeveloped nations. Aim of the study: To assess the efficacy of DCT and SPECT/MRI in the diagnosis and localization of breast cancer. Subjects and methods: In this study, 34 female patients with suspected breast cancer who were referred to the radiology departments of two hospitals—Almana General Hospital in Khobar, Kingdom of Saudi Arabia KSA, and the National Cancer Institute (NCI) Cairo—from surgical departments and outpatient clinics were included. The study ran from March 2018 to February 2023. Digital tomography (DBT) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) were administered to all patients. Results: Comparing DBT with DCE-MRI for BIRAD category assessment yields a highly significant difference (P-value=0.001). Our study found that 73.3% of breast lesion BIRAD scores were upgraded and 2.96 percent were downgraded when using DCE-MRI instead of DBT. This study found no statistically significant distinction between BDT and DCE-MRI in terms of site, shape, margin, and focality (all with p-values>0.05). Conclusion: Significantly higher diagnostic performance of DCE-MRI using qualitative and quantitative assessment in diagnosis and Bi-RAD categorization of breast carcinoma with high sensitivity, specificity, accuracy, PPV, and NPV as compared to DBT. DCE-MRI Bi-RAD categorization was essential for management of breast carcinoma. Dynamic MRI was more sensitive for detection of axillary adenopathy as compared to Tomosynthesis. | ||
| Keywords | ||
| Malignant Breast Cancer; Digital Tomosynthisis; Enhanced MRI | ||
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