Genetic Diversity of Some Proteus mirabilis Strains Isolated from Gastric Discorded Egyptian Patients.
Fahmy, N., El-Shibiny, A., Abdel-Raouf, M., Y. A, O. (2020). Genetic Diversity of Some Proteus mirabilis Strains Isolated from Gastric Discorded Egyptian Patients.. EKB Journal Management System, 47(2), 7-17. doi: 10.21608/mjb.2020.462393
Nada A. Fahmy; Ayman El-Shibiny; Mohamed Abdel-Raouf; Osman, Y. A. "Genetic Diversity of Some Proteus mirabilis Strains Isolated from Gastric Discorded Egyptian Patients.". EKB Journal Management System, 47, 2, 2020, 7-17. doi: 10.21608/mjb.2020.462393
Fahmy, N., El-Shibiny, A., Abdel-Raouf, M., Y. A, O. (2020). 'Genetic Diversity of Some Proteus mirabilis Strains Isolated from Gastric Discorded Egyptian Patients.', EKB Journal Management System, 47(2), pp. 7-17. doi: 10.21608/mjb.2020.462393
Fahmy, N., El-Shibiny, A., Abdel-Raouf, M., Y. A, O. Genetic Diversity of Some Proteus mirabilis Strains Isolated from Gastric Discorded Egyptian Patients.. EKB Journal Management System, 2020; 47(2): 7-17. doi: 10.21608/mjb.2020.462393

Genetic Diversity of Some Proteus mirabilis Strains Isolated from Gastric Discorded Egyptian Patients.

Mansoura Journal of Biology
Volume 47, Issue 2, June 2020, Pages 7-17    PDF (976.56 K)
Document Type: Research Article
DOI: 10.21608/mjb.2020.462393
Authors
Nada A. Fahmy1; Ayman El-Shibiny1; Mohamed Abdel-Raouf2; Osman, Y. A* 3
1Center for Microbiology and Phage Therapy, Zewail City of Science and Technology, Egypt, 12578
2Gastroenterology Surgical Center (GEC), Mansoura University, Mansoura, Egypt,
3Faculty of Science, Mansoura University, Mansoura, Egypt, 35516
Abstract
Proteus mirabilis (P. mirabilis) is a member of the Enterobacteriaceae family that is linked to the increased risk of pathogenicity and acquisition of antibiotic resistivity. Moreover, P. mirabilis is common in urinary tract infection, it is also considered a potential gut pathogen that has an etiological role in Inflammatory bowel disease (IBD). The IBD that represented any inflammation occurred prolonged the gastrointestinal tract. This study includes a clinical survey for a group of sixty-eight patients with different gastric disorder diseases, aged ranges between 5 and 76 years, (61.77%) were females and (38.23%) were males. Only twenty-eight (41.18%) of patients were positive for P. mirabilis infection. Our results demonstrated a significant relation between P. mirabilis infection and colitis (P > 0.05). The Molecular analysis indicated that from the 28 isolates only four strains of P. mirabilis were chosen due to their distinction; they were isolates 2, 10, 16 and 23.  More importantly, P. mirabilis isolate 10 was the most frequent one. Also, the in-vitro antibiotic sensitivity of the four isolates indicated their resistance to β-lactams, fluoroquinolones, sulfonamides and chloramphenicol classes of antibiotics. In conclusion, P. mirabilis is linked to gastric disordered diseases prevalent among Egyptian patients.
Keywords
Proteus mirabilis; Gastrointestinal Discorders
Statistics
Article View: 2
PDF Download: 1