Aflatoxin in Infant Milk Formulae: Potential Mutagenicity and Management | ||
| Mansoura Journal of Biology | ||
| Volume 46, Issue 1, March 2020, Pages 19-25 PDF (794.02 K) | ||
| Document Type: Research Article | ||
| DOI: 10.21608/mjb.2020.462405 | ||
| Authors | ||
| G.M. Abdel-Fattah* 1; M. I. Soliman1; E. E. Hafez2; H. S. El-Sherbeiny1 | ||
| 1Botany Department, Faculty of Science, Mansoura University | ||
| 2Molecular Plant Pathology Department, City for Science and Technology Applications | ||
| Abstract | ||
| (The main purpose of this study was to investigate the aflatoxin M1 (AFM1) presence in infant milk formulae and aimed also to study its cytotoxic and genotoxic effect using a test plant, Allium cepa and also to manage AFM1 production using different essential oils of some Egyptian higher plants. The study was conducted in Faculty of Science, Mansoura University. A total of 10 samples were collected from different pharmacies to screen the presence of AFM1 in three exposure times, 0, 15 and 30 days from the opening of the formulae using the enzyme-linked immunosorbent assay (ELISA). The amount of AFM1 ranged from 887 to 1125 pg/ml. The study also aimed to isolate the fungi found in the baby milk responsible for the AFM1 production. Aspergillus flavus, A. parsiticus and Pencillium species. are some of the mycoflora isolated from the studied formulae. After that, isolation of the AFM1 using GC-MS (Gas Chromatography Mass Spectrometry) was conducted in central laboratory, the City for Scientific Research and Technology Applications. | ||
| Keywords | ||
| Aflatoxin M1; ELISA; Essential oils; Aspergillus flavus | ||
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