The Clinical and Angiographic Outcomes of Routine Post-Dilatation after Primary Percutaneous Coronary Intervention in Patients with Acute ST-elevation Myocardial Infarction | ||
| Zagazig University Medical Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 28 October 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2025.384310.3946 | ||
| Authors | ||
| Abdelrahman Ahmed Adel1; Mohammad Hossam El-Din El-Shaer2; Fadwa Hamed Mahmoud* 3; Baher Nabil Eldesouky Nashy4 | ||
| 1Lecturer of Cardiology Department, Faculty of Medicine, Zagazig university, Egypt | ||
| 2Professor of Cardiology Department, Faculty of Medicine, Zagazig university, Egypt | ||
| 3Department of Cardiology, Faculty of Medicine, Omar Al-Mukhtar University-Libya | ||
| 4Assistant Professor of Cardiology Department, Faculty of Medicine, Zagazig university, Egypt | ||
| Abstract | ||
| Background: Primary percutaneous coronary intervention remains the preferred and guideline-recommended reperfusion strategy for patients presenting with acute ST-segment elevation myocardial infarction (STEMI), as it promptly restores blood flow by reopening the infarct-related coronary artery, thereby limiting myocardial damage. This study aimed to Improving outcome of the patients with ST-elevation myocardial infarction after PCI. Methods: This Prospective cohort study included 120 patients diagnosed with acute STEMI and undergoing PCI were randomized into two groups: Group I (PDgroup) included 60 patients who underwent post-dilatation after primary PCI. Group Ⅱ (NPD group) includes 60 patients who underwent primary PCI with no post-dilatation. Results: The primary outcome showed significant findings: Major adverse cardiovascular events (MACE) occurred in 3.3% of the PD group and 16.7% of the NPD group, with no fatalities in either group. Target vessel revascularization (TVR) and acute stent thrombosis occurred in 1.7% and 1.7% in the PD group, and 8.3% and 1.7% in the NPD group, respectively. No significant differences were found except for MACE. For secondary outcomes, 25% of NPD patients experienced acute coronary syndrome versus 8.3% in the PD group (P=0.03), indicating a significant difference. Angiographic outcomes also revealed a significant difference in TIMI flow, with 11.7% of NPD patients showing no reflow compared to 1.7% in the PD group (P=0.046). Conclusion: The postdilation strategy in primary PCI in patients with STEMI tends to reduce MACE as primary outcome, reduce the ACS events after PCI as secondary outcome and reduce the incidence of no reflow/TIMI 0-1 as angiographic outcome | ||
| Keywords | ||
| ST-elevation myocardial infarction; TVR; Percutaneous coronary intervention | ||
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