evaluation of antibiotic resistance in staphylococcus aureus strains isolated from mansoura university hospitals | ||
| Mansoura Journal of Biology | ||
| Volume 45, Issue 4, December 2019, Pages 1-7 PDF (579.47 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjb.2019.462670 | ||
| Authors | ||
| Attiya Hamed Mohamedin; Ashraf Elsayed; Hanan Mohammed Naser* | ||
| Botany Department, Faculty of Science, Mansoura University, 35516 Mansoura City, Egypt | ||
| Abstract | ||
| The introduction of antibiotics revolutionized medicine in the 20th-century permitting the treatment of incurable infections. Widespread use of antibiotics has led to the development of resistant microorganisms. Lately, there is increase in community and hospital-acquired infections accompanied by Multi-drug-resistant (MDR) Staphylococcus aureus. The goal of this study is evaluating the features of antibiotic resistance of S. aureus isolates through two years in different clinical samples from Mansoura University Hospitals. Fourty five clinical Staphylococcus aureus isolates were collected from patients from Mansoura University Hospitals; Emergency, Mansoura University, Pediatric, Specialized medical and Ophthalmic. Multidrug resistant S.aureus (MDR) isolates showed varible resistances to Clindamycin (84.45%), Ciprofloxacin (75.55%), Norfloxacin (75.55%), Ofloxacin (73.33%), Erythromycin (66.68%), Gatifloxacin(60%), Levofloxacin (57.79%), Gentamycin (53.34%), Rifampin (46.66%), Linezolid (06.66%), Vancomycin (04.45%) antibiotics. In conclusion, the MDR S. aureus isolated from Mansoura University Hospitals showed high resistance to nine antibiotics and low resistance to Vancomycin and Linezolid. Reducing the average of antibiotic resistance contributes in decreasing therapy cost. Through the years any variation of antibiotic resistance must be determined, and for guiding empirical therapies every hospital must define its own antibiotic resistance profile. | ||
| Keywords | ||
| Staphylococcus aureus; clinical isolates; Antibiotic resistance | ||
|
Statistics Article View: 1 PDF Download: 1 |
||
