Effect of moringa extract against renal injury caused by high fat diet induced obesity in male rats | ||
| Mansoura Journal of Biology | ||
| Volume 44, Issue 3, September 2019, Pages 34-38 PDF (757.13 K) | ||
| Document Type: Research Article | ||
| DOI: 10.21608/mjb.2019.462692 | ||
| Authors | ||
| Azza I Othman1; Maher A Amer1; Asmaa S Basos* 2 | ||
| 1Zoology Department, Faculty of science, Mansoura University, Mansoura, Egypt | ||
| 2Zoology Department, Faculty of science, Azzytuna University, Tarhuna Libya Physiology Division, Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt | ||
| Abstract | ||
| The study was performed to study the influence of moringa extract against renal injury caused by high fat diet in male rats. Rats randomly were divide into six groups, six animals each as following: group 1: rats not received any tratment; group 2: rats received moringa extract (ME) (300mg/kg b w) daily for 8 wks.; group 3 : rats of this group fed on HFD daily for 8 wks.; group 4: rats of this group fed on HFD concomitant with ME (300 mg/kg bw) for daily for 8 wks.; group 5: rats of this group fed on HFD concomitant with SIM (40 mg/kg bw) daily for 8 wks.; group 6: rats of this group fed on HFD concomitant with ME (300 mg/kg bw) and SIM (40 mg/kg bw) daily for 8 wks. Our results proved that the administration of high fat diet fulfilled significant rise in MDA. However, marked reduction in GSH, TAC, SOD, CAT ,GSH-Px, and GSH-Rd On the other side, the administration ME improved the deviations resulted from HFD | ||
| Keywords | ||
| Moringa; high fat diet; renotoxicity | ||
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