Efficacy of Diluted Betadine vs. Antibiotic Installation Before Surgical Wound Closure in Prevention of Post-Cardiac Surgery Wound Infection | ||
| Journal of Current Medical Research and Practice | ||
| Volume 10, Issue 4, October 2025, Pages 197-204 PDF (383.96 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jcmrp.2025.362777.1218 | ||
| Authors | ||
| Abdelrahman Hamed Ahmed Mohamed* 1; Ahmed Mohamed Kamal El-Minshawy1; Mohamed Hassan Osman Hasan2; Ahmed Mohamed Abdelhakim Mekkawy1 | ||
| 1Department of Cardiothoracic Surgery, Faculty of Medicine, Assiut University, Assiut, Egypt. | ||
| 2Department of General Surgery, Faculty of Medicine, Assiut University, Assiut, Egypt. | ||
| Abstract | ||
| Abstract: Purpose: This study evaluated the efficacy of intraoperative, pre-closure diluted Betadine versus powdered vancomycin in preventing surgical site infections (SSIs) in post-cardiac surgery patients undergoing median sternotomy. Methods: A retrospective study was conducted on 90 patients (12 months to 65 years) undergoing primary sternotomy. Patients were divided into three groups: Group A (3.5% diluted Betadine), Group B (powdered vancomycin), and Group C (placebo). Wound healing and infection outcomes were assessed over a two-month follow-up period. Results: The Betadine group had the lowest SSI rate (6.7%), significantly lower than the vancomycin group (43.3%) and the control group (23.3%). SSIs were primarily superficial, except for two deep wound infections in the control group. The duration of the procedure and sternal healing did not differ significantly between the groups. However, in the Betadine group, higher patient weight was significantly correlated with an increased risk of infection. No such correlations were found in the vancomycin group. All the patients showed good healing signs in the Betadine and vancomycin group compared to the control group. Conclusions: 3.5% diluted Betadine reduced superficial SSIs following median sternotomy more effectively than vancomycin and placebo. While no significant difference existed between the intervention group in the case of deep wound infection, both showed lower DSWI rates than the Placebo. Betadine demonstrated superior infection prevention, particularly regarding superficial infections. | ||
| Keywords | ||
| Keywords: Superficial sternal wound infection (SSWI); Deep sternal wound infection (DSWI); Cardiac surgery; Median sternotomy; Diluted Betadine; Vancomycin; Wound closure | ||
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