Comparing Planimetry-based ImageJ Analysis and Vitiligo Extent Score for a Target Area (VESTA) in Assessing Vitiligo Treatment outcomes | ||
| Minia Journal of Medical Research | ||
| Articles in Press, Accepted Manuscript, Available Online from 30 October 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjmr.2025.432928.2108 | ||
| Authors | ||
| Rasha Turky Abdel-Razek1; Mahmoud Mahmoud Mostafa Mahmoud2; Tasneem Mohammed Mortada* 1; Ahmed Ahmed Touni3 | ||
| 1Department of Dermatology and Venereology, Faculty of Medicine, Minia University, Minia, Egypt. | ||
| 2Department of pharmaceutics Faculty of Pharmacy - Minia University -Minia, Egypt. | ||
| 3Dermatology Department, Faculty of Medicine, Minia university, Minia, Egypt. | ||
| Abstract | ||
| Abstract Background: Vitiligo is a common acquired pigmentary disorder that presents as progressive loss of functioning melanocytes. Since localized treatment for vitiligo is as essential as systemic treatment, an accurate instrument for target evaluation is needed besides those for whole body evaluation. Several digital image analysis systems have been developed for surface calculation of vitiligo lesions. Critical assessment of their measurement properties is crucial to support evidence-based recommendations on the most suitable instruments and will reveal the need for future research. Aim of the work: The aim of this study is to assay the accuracy of the digital planimetry techniques using imageJ software and comparing it with other clinical evaluation methods, such as the Vitiligo Extent Score for a Target Area (VESTA), for estimating vitiligo surface areas. Methods: A total of 46 vitiligo lesions from 20 patients were treated with dermabrasion. The lesional areas were evaluated using two different methods: the VESTA score and planimetry-based analysis via ImageJ (Mannual tracing on transparent sheets combined with digital measurments) for comparative assessment. Evaluation was performed at a baseline and repeated 3 months after the procedure. Results: Both measurement methods; ImageJ software and VESTA score; demonstrated a high level of agreement in the percentage of improvement when assaying treatment response (41.9±32.4 and 41.8±33.4 respectively). No significant difference was found between the two methods (p>0.05). Conclusion: Planimetry-based ImageJ software for surface area measurement is a reliable and precise method for assessing the treatment response of target lesions, showing comparable accuracy to the VESTA score. | ||
| Keywords | ||
| Keywords: Digital planimetry analysis; imageJ software; VESTA score; Dermabrasion; Vitiligo | ||
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