Correlation of COVID-19 and development of new onset diabetes mellitus and its possible pathogenesis | ||
| Benha Medical Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 01 November 2025 PDF (587.49 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bmfj.2025.341658.2273 | ||
| Authors | ||
| Medhat Abd Elmonem Ali Khalil1; Nabil khattab1; Ali El Sayed Ali2; Ahmed Mohamed Aly Mostafa* 3; Mohammed Ahmed Mohammed4 | ||
| 1Department of internal medicine, Faculty of medicine, Benha University | ||
| 2Department of internal medicine, Faculty of medicine, Benha University | ||
| 3M.B.B.CH of internal medicine, Faculty of medicine, Alexandria University | ||
| 4Department of internal medicine, faculty of medicine, Benha university, Benha, Egypt | ||
| Abstract | ||
| Background: The severe acute respiratory syndrome-coronavirus (SARS-CoV)-2 was the cause of the pandemic known as coronavirus disease-19 (COVID-19). One of the main metabolic diseases that contribute to death and morbidity worldwide is diabetes. This study aims to evaluate the likelihood of developing new-onset diabetes mellitus in COVID-19-infected patients and its possible pathogenesis. Patients and Methods: This cross-sectional study was conducted at Ashmoun Fever Hospital and Menouf Fever Hospital on 100 cases with confirmed COVID-19 admitted and managed in an inpatient ward and isolated ICU department for 6 months started in December 2020 to July 2021. Results: This study enrolled 100 cases with confirmed COVID-19. There was a highly significant variance between severe to critical than in the mild to moderate group about age, male gender, ICU admission, death, CRP, d dimer, ferritin, FBG, and HbA1c as they were higher in severe to critical than in mild to moderate. There was a high statistically significant relation between FBG and Duration of ICU, Ferritin, Smoking, Cholesterol, TG, HDL, LDL, HbA1C, D-dimer, and severity of COVID-19. Conclusion: Hyperglycemia was linked to poor outcomes in COVID-19 cases. Baseline hyperglycemia levels were a major predictor for mortality among cases admitted immediately to the ICU. | ||
| Keywords | ||
| COVID-19; diabetes; glucose; hospital; mortality | ||
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