Effect of Addition of Omega-3 Fatty Acids to Nano-Hydroxyapatite on its Physical Properties: An In-Vitro Study | ||
| Ain Shams Dental Journal | ||
| Volume 38, Issue 2, June 2025, Pages 591-600 PDF (1.21 M) | ||
| Document Type: Original articles | ||
| DOI: 10.21608/asdj.2024.300214.1343 | ||
| Authors | ||
| Amira Gareer1; Tarek Medhat Elsewify2; Mohamed Mokhtar Nagy* 3; Salma Hassan El-Ashry4; Ahmed Abd Elrahman Hashem1 | ||
| 1Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt. | ||
| 21- Department of Restorative Dental Sciences, College of Dentistry, Gulf Medical University, Ajman, UAE. 2- Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt. | ||
| 31- Department of Endodontics, Faculty of Dentistry, Al Galala University, Suez, Egypt. 2- Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt. | ||
| 4Department of Endodontics, Faculty of Dentistry, Ain Shams University, Cairo, Egypt | ||
| Abstract | ||
| Aim: This study evaluated the physical properties of nano-hydroxyapatite (nHA) after the addition of Omega-3 (ꞷ3) powder in terms of radiopacity, solubility & pH. Materials and methods: Radiopacity of group I (nHA), group II (2nHA:1ꞷ3), & group III (1nHA:1ꞷ3) were digitally evaluated against aluminium step wedge, human dentin & bovine cortical bone. Solubility of Calcium (Ca2+) was evaluated after 1,3 & 5 days in Tris-HCL solution of 7.4 pH & Citric Acid solution after 5 days using atomic absorption spectroscopy. pH was evaluated along with the solubility test in Tris-HCL at 0h, 1, 3 & 5 days. Results: The highest radiopacity level was recorded in nHA group. While groups containing ꞷ3 showed the least mean grey value. Solubility of Ca2+ ions increased with the increase in immersion time & with the decrease in the pH of the solution. In both solutions, group III showed the greatest mean of Ca2+ concentration released followed by group II & group I during all observation periods. In Tris-HCL, initial rise in pH up to 7.94 was observed in group I at 0h followed by a gradual drop reaching a pH value of 6.72 at day 5. While in groups II & III, pH showed an initial decrease at 0h, a gradual increase followed from day 1 to 5. Conclusion: Adding (ꞷ3) to (nHA) lowered its radiopacity and increased its solubility in Tris-HCL & acidic medium. (nHA) calcium release was not affected by low pH, offering a clinical advantage in case of bacterial infection. | ||
| Keywords | ||
| Nano-Hydroxyapatite; Omega-3; Radiopacity; Calcium Solubility; pH | ||
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