Knowledge of Parents of Thalassemic Children about level of Hypertriglyceridemia and Iron Overload on Growth& Schoolar Performance | ||
| Medicine Updates | ||
| Articles in Press, Accepted Manuscript, Available Online from 02 November 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/muj.2025.430487.1269 | ||
| Authors | ||
| Sonia Gamal Elsharkawy1; Ahmed Darwish Mohamed2; Basma Badreldin Bader Eldine3; Mayada Anwar Mohamed4; Dina Ahmed Elbayaa* 5 | ||
| 1Department of pediatrics Faculty of Medicine, Port said University faculty of medicine Port Said University | ||
| 2Pediatrics and Neonatology, Faculty of Medicine, Mansoura University, Mansoura, Egypt. | ||
| 3PProfessor of Clinical pathology, Faculty of Medicine, Port Said University, Port Said, Egypt.ort said university | ||
| 4Pediatrics and Neonatology Department, Al-Salam Hospital, Port Said, Egypt. | ||
| 5faculty of medicine Port Said University | ||
| Abstract | ||
| Background:Background: Patients with beta thalassemia have higher risk of metabolic disturbances as hypertriglyceridemia which increases the risk of cardiovascular disease. Together with iron overload and bone-deforming marrow expansion can affect bone growth and school performance. Aim of the study: To assess the parent's knowledge regarding association between level hypertriglyceridemia, high serum ferritin and their affection on patients' growth and school performance. Methods: This cross-sectional study included 35 thalassemia patients who were following at the Pediatric Hematology Outpatient Clinic at El-Tadamon Hospital, Port Said Governorate, during the period from January 2025 to July 2025. All children were subjected to full history taking, clinical examination, including assessment of growth by weight, height, BMI and laboratory investigations including assessment of serum triglyceride and serum ferritin, assessment of school performance, quality of life , and knowledge by well-formed questionnaire. Results: 48.6% had satisfactory knowledge about thalassemia while 51.4% had unsatisfactory knowledge. Most children (65.7%) had poor QOL, while 34.3% had good QOL, 31.3% of children had hypertriglyceridemia. Children with irregular school attendance and learning difficulty had higher serum triglyceride levels. Children with irregular school attendance, learning difficulties and those with growth retardation had higher ferritin compared to others. Triglycerides had significant positive correlation with (BMI, and serum ferritin). Conclusions: hypertriglyceridemia and Iron overload were associated with bad impact on growth and school performance in children with thalassemia. Triglycerides had significant positive correlation with body mass index and serum ferritin. Total knowledge score of the patient’s parents correlates positively with total quality of life score. | ||
| Keywords | ||
| Thalassemia; Hypertriglyceridemia; Scholar Performance | ||
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