Effect of Glucosamine, Chondroitin and Some Herbs Extract Phonophoresis in the Treatment of Grade I and II Knee Meniscal Injuries: a Randomized Placebo-controlled Clinical Trial | ||
| Benha International Journal of Physical Therapy | ||
| Articles in Press, Accepted Manuscript, Available Online from 03 November 2025 PDF (482.32 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bijpt.2025.389395.1093 | ||
| Authors | ||
| Eslam Elsayed Shohda* 1; Reda Sheta2 | ||
| 1general organization for teaching hospitals and institutes | ||
| 2Orthopedics; Al-Ahrar teaching Hospital, Zagazig, Al-Sharkia, Egypt | ||
| Abstract | ||
| Background: Among knee pathologies managed within musculoskeletal medicine, meniscal injuries are notably prevalent. objective: to determine the effects of glucosamine, chondroitin, and some herb extracts administered through phonophoresis (PH) as a therapeutic modality for knee meniscal lesions of diagnosed severity of both Grade I and II. Methods: A single-blind, randomized controlled trial incorporating a placebo arm was conducted. (allocation ratio 1:1:1) was implemented at the physiotherapy outpatient department of Alahrar Teaching Hospital, Egypt. Fifteen patients (group A) received phonophoresis using glucosamine, chondroitin, and herbal extracts (1 W/cm², 1 MHz, 5 minutes continuous, 5 minutes pulsed). Fifteen patients (group B) received therapeutic ultrasound with the same parameters. Fifteen patients (group C) received sham ultrasound (massage using the head of the ultrasound). Treatment was conducted over twelve successive sessions. The Numeric Rating Scale (NRS) was employed to measure the intensity of pain. Knee functional impairments were evaluated using the WOMAC scale. Results: A statistically significant relief was observed in pain and knee functional disabilities for all groups. There was no statistically significant difference between groups A and B regarding the examined parameters. Statistically significant differences in pain and knee functional disabilities were noted between groups A and C, in addition to those between groups B and C. Conclusion: The study results propose that the application of ultrasound, using a gel containing glucosamine, chondroitin, and some herbal extracts, or using raw gel significantly improves pain and knee function compared to placebo in managing Grade I and II tears of the knee meniscus. | ||
| Keywords | ||
| Ultrasound; Physiotherapy; Rehabilitation and Meniscal degeneration | ||
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