Pattern of Cardiac Affection among Down Syndrome Pediatric Patients Attending Assiut University Children's Hospital | ||
| Journal of Current Medical Research and Practice | ||
| Volume 10, Issue 4, October 2025, Pages 215-224 PDF (686.54 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jcmrp.2024.296074.1076 | ||
| Authors | ||
| Amira G. Osman* 1; Hekma Saad Farghaly2; Shaimaa M. Khalaf2; Dalia G. Mahran3 | ||
| 1Department of Family Medicine, Faculty of Medicine, Assiut University, Assiut, Egypt. | ||
| 2Department of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt. | ||
| 3Department of Public Health and Community medicine, Family Medicine Department, Faculty of Medicine, Assiut university, Assiut, Egypt. | ||
| Abstract | ||
| Abstract: Aim: The study aims to evaluate the pattern of cardiac affection in pediatric DS patients. Methods: From February 2022 to June 2023, a tertiary University Hospital conducted a descriptive prospective case series study involving 102 children. The socio-demographic characteristics, marital history, and examination were all included in the questionnaire. Results: In total, 102 children with DS were recruited for this study. A total (45.1%) patients had clinical cardiac affection, and (54.90%) without cardiac affection. The majority of participants were < 1 year old (63.7%), males (58.8%), and the majority of patients came from rural areas (87.3%). The majority of mothers were multiparous (27.45%). The current study found that the mother's age was not a risk factor for Down syndrome, as the study revealed a median maternal age of 35.5(18-50), because translocations usually occur at a young age. Both groups had insignificant differences regarding demographics, obstetric and comorbidities, except residence, where the majority of both groups came from rural areas with a higher frequency of rural residency among those without cardiac affection (94.65 vs. 78.3%; p= 0.01). The current study found that the most frequent cardiac lesions were ASD with VSD (AVSD), which were present in (52.17%) children, isolated ASD (15.2%), isolated VSD (6.5%), and VSD& PFO (6.5%). Conclusions: Both cardiac and non-cardiac DS children had insignificant differences with regard to demographic and anthropometric measurements. Primary health care has become essential to help these children have longer, more productive lives, with more attention to growth. | ||
| Keywords | ||
| Keywords: Pattern of Cardiac affection; Down Syndrome; Assiut University Hospital | ||
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