Role of Vitamin D in Dementia in a sample of Egyptian patients | ||
| Al-Azhar International Medical Journal | ||
| Volume 2025, Issue 7, July 2025, Pages 65-71 PDF (400.53 K) | ||
| Document Type: Original Article | ||
| DOI: https://doi.org/10.21608/aimj.2025.446638 | ||
| Authors | ||
| Hassan Kawashty Gad Hussien1; Mohammad Ali Saeed Hassan2; Adel Mahmoud Mohamed Abdou3; Ahmed Elsaid Elsayed Mohammed4; Mohammed Saeed Hassan5; Mahmoud Ashraf Abdelmonem Mahmoud* 6 | ||
| 1Professor of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| 2Assistant Professor of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| 3Assistant Professor of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| 4Assistant Professor of Neurology, Military Medical Academy, Cairo, Egypt | ||
| 5Lecturer of Neurology, Military Medical Academy, Cairo, Egypt | ||
| 6MBBCh., Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| Abstract | ||
| Background: In order for the body to absorb calcium and phosphate, vitamin D—a steroid hormone—is essential. Two primary forms of vitamin D, vitamin D3 and vitamin D2, make up the inactive form of vitamin D. The skin produces vitamin D3, also known as cholecalciferol, when exposed to ultraviolet light, vitamin D3 supplements, or foods that are fortified with vitamin D. Aim and objectives: To define the relation between vitamin D and dementia among the Egyptian population. Patients and methods: This was a retrospective, case control study that was conducted at El-Hussein University hospital and Kobri El-koba military complex on 50 patients with a diagnosis of dementia and control group of 50 healthy individuals of similar age and gender. Results: The present study's most noteworthy discovery was that the dementia group had significantly reduced serum 25(OH)D levels (20.88±5.91 ng/ml) in comparison to the control group (41.28±7.21 ng/ml). Conclusion: Our study demonstrated compelling evidence for an association between low vitamin D levels and an increased risk of dementia among the Egyptian population. | ||
| Keywords | ||
| Vitamin D; Dementia; Egyptian patients | ||
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