The Effectiveness of Platelet-Rich Plasma in Wound Healing of Pilonidal Sinus with Karydakis Procedure | ||
| The Egyptian Journal of Surgery | ||
| Volume 44, Issue 4, October 2025, Pages 1123-1128 PDF (463.28 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejsur.2025.356743.1374 | ||
| Authors | ||
| Ehab Abdel Meguid Loutfy Hussein; Hossam E. Elshafey; Moamen Elsayed Elbadawy* ; Yasser Baz; Mohamed Mahmoud Ezzat | ||
| Department of General Surgery, Faculty of Medicine, Helwan University, Helwan, Egypt | ||
| Abstract | ||
| Background: Sacrococcygeal pilonidal sinus (SPD) is a common disease affects young individuals, especially men. Management includes non-surgical and surgical methods. PRP therapy is a recent method that shows promise in decreasing recurrence rates and speeding up wound healing. This study evaluates PRP's potential in healing PNS wounds. Patients and Methods: The study was a prospective study at Helwan University Hospital involved 48 patients with pilonidal sinus disease, comparing primary closure alone (Group A) to primary closure with PRP injections (Group B). Patients were randomized, and PRP was injected during surgery and on postoperative days 7 and 14 with regular followups assessed pain and wound healing. Results: Patients of PRP injection group showed statistically significantly shorter healing time, lower pain scores, fewer drainage days, and quicker return to work. Complications were similar between groups. Conclusion: The use of PRP in treatment of SPD clinically reduces healing and recovery time, and lowers economic burden, thus should be routinely offered. | ||
| Keywords | ||
| Karydakis procedure; pilonidal sinus; platelet-rich | ||
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