The Role of Sentinel Lymph Nodes Biopsy Using Blue Dye in the Management of Papillary Thyroid Carcinoma, a Case Series | ||
| The Egyptian Journal of Surgery | ||
| Volume 44, Issue 4, October 2025, Pages 1184-1189 PDF (309.08 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejsur.2025.362348.1402 | ||
| Authors | ||
| El-Sayed Mahmoud Abd-El-Wahab1; Ahmed Mohamed Said Mohamed2; Zahra Ali Salem Abualrebagi* 1 | ||
| 1Department of General Surgery, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt. | ||
| 2Department of General Surgery, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.. | ||
| Abstract | ||
| Background: The thyroid gland plays a pivotal role in regulating metabolism through the production of thyroid hormones. As the prevalence of thyroid carcinoma continues to rise globally, with varying histological subtypes such as papillary, follicular, medullary, and anaplastic thyroid cancers, the management landscape becomes increasingly intricate. Aim and objectives: In order to determine whether sentinel lymph nodes biopsy (SLNB) is a viable and effective method for treating papillary thyroid cancer that has not spread to regional lymph nodes, and to decrease the likelihood of needless lymph node distention in these patients, we will examine its practicality and clinical effectiveness. Patients and methods: Twenty (20) patients with a diagnosis of papillary thyroid cancer (PTC) participated in the current prospective study, which ran from November 2023 to November 2024 in the General Surgery Department of Al-Zahraa University Hospital. Results: With a sensitivity of 92.3% (12/13*100), specificity of 100% (3/3*100), positive predictive value of 100% (12/12*100), and negative predictive value of 75% (3/4*100), SLN is a very successful model. Roughness level is 93.8%. Only 6 patients did not have true LN disease, whereas 14 patients did. There were a total of three instances of negative SNL and NSLN, with three, one, and zero cases of genuine negative, false negative, and false positive, respectively. Conclusion: Using the blue dye technique for identifying sentinel lymph nodes in patients with non-metastatic papillary thyroid carcinoma has a 75% success rate (12/16). However, further studies on larger numbers of patients are needed to confirm the outcomes of this study. | ||
| Keywords | ||
| Blue dye; PTC; SLNB | ||
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