The value of Copeptin and Lung Ultrasound in Assessment of Volume Status in Chronic Regular Hemodialysis Patients | ||
| Al-Azhar International Medical Journal | ||
| Volume 2025, Issue 7, July 2025, Pages 147-152 PDF (295.86 K) | ||
| Document Type: Original Article | ||
| DOI: https://doi.org/10.21608/aimj.2025.446651 | ||
| Authors | ||
| Al Sayed Mohamed Rashed1; Hazem Sayed Ahmed Ayoub1; Fareed Shawqi Basiony2; Abd El Salam Fathy Abd El Salam3; Ibrahim Abd Elwhab Elnewishy* 1 | ||
| 1Department of Internal Medicine and Nephrology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt. | ||
| 2Department of Chest diseases, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt. | ||
| 3Department of Clinical Pathology, Faculty of Medicine for Boys, Al-Azhar University, Cairo, Egypt | ||
| Abstract | ||
| Background: Research indicates that copeptin levels are raised in cases with end-stage kidney disease (ESKD) and may serve as an alternate biomarker to vasopressin for predicting cardiovascular illnesses and death in end-stage kidney disease cases. Aim: To assess the role of lung ultrasound and Copeptin in the assessment of volume status before and after a dialysis session in hemodialysis cases. Patients and methods: The cross-sectional investigation comprised ninety cases of patients who had been diagnosed with chronic renal failure on regular dialysis and fulfilled the selection criteria from the Nephrology Unit, Al Hussein University Hospital. This was a prospective observational investigation performed at the Department of Internal Medicine, Faculty of Medicine, Al-Azhar University. Results: A significant reduction has been observed in copeptin level post-hemodialysis than pre-hemodialysis (p<0.001). There was a significant positive association among copeptin, SBP, DBP, body weight, B-line score, and IVC diameter (p <0.001). There was a significant negative association between copeptin and IVC Collapsibility (p <0.001). Conclusion: In summary, Copeptin and lung ultrasonography can evaluate fluid volume status. This provides an effective approach for assessing fluid status in cases with volume overload. Future directions could involve the expansion and application of lung ultrasonography and Copeptin for the quantitative assessment of volume status in additional volume-sensitive populations, like cases with heart failure. | ||
| Keywords | ||
| Copeptin; Lung Ultrasound; Hemodialysis; ESKD | ||
|
Statistics Article View: 3 PDF Download: 4 |
||
