Effect of Bariatric Surgery Versus Insulin Sensitizers on Ovulation in Poly-Cystic Ovary Patients | ||
| Evidence Based Women's Health Journal | ||
| Volume 15, Issue 15, January 2025, Pages 1-8 PDF (388.77 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ebwhj.2025.375966.1452 | ||
| Author | ||
| Wael Samir Elgazayerli* | ||
| Obstetrics and gynaecology Alexandria University | ||
| Abstract | ||
| Objectives : to evaluate the effect of laparoscopic sleeve gastrectomy versus insulin sensitizers on both resumption of ovulation and insulin resistance within a period of six months in patients with poly cystic ovarian syndrome Study design: This prospective randomized cohort study was conducted at Alexandria Main University Hospitals (El Shatby Hospital), Egypt from February 2022 until February 2023. Results: While bariatric surgery has been demonstrated to benefit PCOS, its effect on infertility caused by PCOS is less clear.(64) Currently, pharmacologic treatments such as metformin are widely used to target insulin insensitivity and lower hyperandrogenism in PCOS, which in turn improves the reproductive symptoms of the disease.(65) Our study revealed that there was improvement of ovulation, fasting insulin level; HOMA-IR and body mass index and percentage of weight loss rated 3 and 6 months post treatment in both study groups but with no significant differences between them. Conclusion:From our study we can conclude that bariatric surgery and insulin sensitizers promote significant weight loss and resumption of ovulation, which is linked to the improvement of Menstrual irregularities, insulin resistance and ovulatory malfunction. Surgery and insulin sensitizers successfully mediate the resolution of PCOS. There was improvement of ovulation, fasting insulin level; HOMA-IR and body mass index and % of weight loss rated 3 and 6 months posttreatment in both study groups but with no significant differences between them Key words : Elshatby University Hospital ; complications ; gynaoncology. | ||
| Keywords | ||
| Elshatby University Hospital; complications; gynaoncology | ||
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