Maternal and Fetal Outcome in Women with First Trimester COVID-19 Infection | ||
| Evidence Based Women's Health Journal | ||
| Volume 15, Issue 15, January 2025, Pages 1-6 PDF (437.2 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ebwhj.2024.291723.1329 | ||
| Authors | ||
| Mostafa Abdelgalil* 1; Emad Salah2; Amr Hassan Hussein Mahmoud3; Nehal Bassiouny4; Asmaa Elsayed Abd Elghane Elsayed5 | ||
| 1Obstetrics and Gynecology department , Kasr Al Ainy hospital, Cairo university | ||
| 2Obstetrics and Gynecology department, Kasr Al Ainy hospital, Cairo university | ||
| 3Obstetrics and Gynecology department, Kasr Al Ainy hospital, Cairo University | ||
| 4Obstetrics and Gynecology department , Kasr Al Ainy hospital, Cairo University | ||
| 5Obstetrics and Gynecology department, El obour hospital | ||
| Abstract | ||
| Background: Coronavirus disease 2019 (COVID-19) is an international public health emergency that is attributed to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Aim: To assess maternal and fetal results in women with COVID-19 infection in the 1st trimester. Patients and Methods: This prospective observational and analytical research was performed on eighty pregnant females infected with COVID-19 in the 1st trimester at the Obstetrics and Gynecology Department, Kasr Al-Ainy Hospital Maternity Hospital, Cairo University. Results: The main pregnancy-associated complications were bleeding in 24 cases (30%), abortion in 20 cases (25%), hyperemesis gravidarum in 1 case (1.3%), hospital admission in 3 cases (3.8%), hypertension/preeclampsia in 10 cases (12.5%), gestational DM in 1 case (1.3%) and preterm premature rupture of membranes (PPROM) in 16 cases (20%). Postpartum hemorrhage occurred in 1 case (1.3%), and 2 cases were admitted to ICU (2.5%). There were 15 preterm neonates (25%) and 45 full-term (75%). The mean birth weight was 2734±797.07 grams, and the median birth weight was 2975 grams (range: 550–4000 grams). The neonatal complications included congenital anomalies in 1 case (1.7%), intrauterine fetal death (IUFD) in 3 cases (5%), neonatal intensive care unit (NICU) in 12 cases (20%), and fetal morbidity in 8 cases (13.3%). Conclusion: During pregnancy, COVID-19 infection is linked to severe maternal and fetal complications. The adverse impacts of COVID-19 through the 1st trimester of pregnancy, where fewer researches have been performed compared to other trimesters, should not be disregarded. | ||
| Keywords | ||
| Acute respiratory syndrome; COVID-19; congenital anomalies; preterm | ||
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