Thoracoscopic Lung Biopsy by Cryomodality versus Electrocautery in Patients with Diffuse Parenchymal Lung Disease | ||
| Al-Azhar International Medical Journal | ||
| Volume 2025, Issue 7, July 2025, Pages 219-224 PDF (315.71 K) | ||
| Document Type: Original Article | ||
| DOI: https://doi.org/10.21608/aimj.2025.446663 | ||
| Authors | ||
| Nabil Farouk Awad1; Mohamed Sami El Hakim2; Moaz Atef Abd El Aty3; Ibrahim El Sayed Ibrahim El Sayed* 4 | ||
| 1Professor of Chest Diseases, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| 2Professor of Histopathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| 3Assistant Professor of Chest Diseases, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| 4MSc, Chest Diseases, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||
| Abstract | ||
| Background: There are about 200 different pulmonary illnesses that can cause diffuse or patchy involvement of the lung parenchyma; these are collectively known as diffuse parenchymal lung disorders (DPLDs). The origin, clinical manifestations, treatment choices, and prognosis of DPLDs vary considerably. Aim and objectives: To compare the safety and effectiveness of two thoracoscopic techniques for the identification of diffuse parenchymal lung disease: cryoprobe and electrocautery. Patients and methods: Taking place between February 2023 and February 2025, this prospective study was carried out in the Endoscopy Unit of the Chest Department at Al-Azhar University Hospitals. Forty patients who underwent comprehensive clinical and investigative evaluation for unconfirmed diagnoses of diffuse pulmonary infiltrates as shown on high resolution computed tomography (HRCT) scans of the chest comprised the study. Results: Hypersensitivity pneumonitis affected 25% of patients, idiopathic pulmonary fibrosis 17.5%, non-specific interstitial pneumonia 15%, sarcoidosis 10%, and adenocarcinoma 10%, according to pathological diagnosis. The study revealed statistically significant differences between the groups, showing that the time for full lung expansion and length of hospital stay were both notably longer in patients who underwent cryo-forceps biopsy. Additionally, the occurrence of air leak was significantly higher among these patients. Conclusion: Medical thoracoscopic lung biopsy, in the hands of experienced interventional pulmonologists, is a practical, safe, effective, and feasible diagnostic procedure.Major complication and longer hospital stays are associated with cryobiopsy, despite the fact that it produces larger and more reliable biopsy samples. Electrocautery is preferable to cryomodality in terms of complications and hospital stay duration. | ||
| Keywords | ||
| Thoracoscopic Lung Biopsy; Cryomodality; Electrocautery; Parenchymal Lung Disease | ||
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