Clinico- laboratory assessment of infantile cholestasis in Fayoum University Hospital | ||
| Fayoum University Medical Journal | ||
| Volume 16, Issue 1, November 2025, Pages 99-108 PDF (591.29 K) | ||
| Document Type: Full Length research Papers | ||
| DOI: 10.21608/fumj.2025.369144.1482 | ||
| Authors | ||
| Yasmin Fathi Elsaid* 1; Manal Anwar Ismail2; Lamiaa Maghawry Ibrahim3; Asmaa Ramadan Mohamed Fawzy3 | ||
| 1pediatric department, faculty of medicine, Fayoum university hosptital, Fayoum | ||
| 2pediatric department, faculty of medicine, Fayoum University Hosptital, Fayoum. Egypt | ||
| 3pediatric department , Fayoum University, Fayoum, Egypt | ||
| Abstract | ||
| Abstract Introduction: Cholestasis occurs during the first three months of life, is characterized as a direct bilirubin level greater than 1 mg/dl when total bilirubin is less than 5 mg/dl or greater than 20% when total bilirubin is greater than 5 mg/dl. Aim of the study: to determine the various cholestasis causes, conduct investigations, and treat newborns that arrive to Fayoum University Children Hospital. Subjects and Methods: A retrospective detailed review of all relevant information from medical records of cholestatic infants presenting to the Hepatology Clinic in Fayoum university hospital during the period from 2016 to June 2023. Data were gathered at Fayoum University Hospital through chart review utilizing the Best-Care system. Results: At presentation the average age was 97.9±164.5 days (range 1-146). At the time of presentation 78% of our infants were in the age group 0-3 months old. Jaundice was the first clinical symptom in 85% of infants that presented with cholestasis with a mean age of onset 20.2±25.6 days. Conclusions: Jaundice was the most common presenting symptom in our cholestatic infants (95%) with mean age of onset 20.2±25.6 days. BA, sepsis and TORCH are the most common etiology. Twenty two of our cases improved with treatment, and twenty seven cases were lost to follow up. | ||
| Keywords | ||
| Keywords: Neonatal Cholestasis; Biliary Atresia; Non biliary atresia | ||
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