Early Identification of Sepsis in the Emergency Department: A Retrospective Audit of Compliance with NICE Guidelines | ||
| The Egyptian Journal of Hospital Medicine | ||
| Volume 101, Issue 1, October 2025, Pages 5469-5474 PDF (712.64 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2025.464805 | ||
| Abstract | ||
| Background: Sepsis can adversely affect the health of hospitalized cases, resulting in elevated morbidity and death rates. It results in major problems for healthcare systems worldwide, resulting in about 11 million mortalities each year. Sepsis Early Alert Tools (SEATs) have emerged as pivotal in expediting the recognition and management of this life-threatening condition. Aim: To assess the impact of implementing a Sepsis Early Alert Tool) SEAT (in the Emergency Department (ED) on compliance with the National Institute for Health and Care Excellence (NICE) protocols for early identification and management of sepsis. Patients and Methods: This was a retrospective audit performed in the ED, evaluating compliance with the NICE protocols for the early identification and management of sepsis prior to and following the implementation of the SEAT. Results: A total of 115 cases have been involved (65 pre-SEAT, 50 post-SEAT). Post-SEAT implementation significantly increased antibiotic administration within 60 minutes of triage (44% vs. 24.6%, p=0.03) and collection of two blood culture sets prior to antibiotics (44% vs. 18.5%, p=0.003). Sequential Organ Failure Assessment scores were lower post-SEAT (2.1 ± 0.77 vs. 2.6 ± 0.66, p≤0.001). Length of stay and mortality showed no significant differences. Conclusion: SEAT implementation improved key sepsis care processes and early recognition, aligning ED practice more closely with NICE guidelines. | ||
| Keywords | ||
| Sepsis; Sepsis Early Alert Tool (SEAT); Emergency Department; NICE Guidelines | ||
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