Prevalence of Blood Protozoa and Impact of Chemotherapy in Exotic Cattle, With Special Reference to Haematological Parameters | ||
| Egyptian Journal of Veterinary Sciences | ||
| Articles in Press, Corrected Proof, Available Online from 09 November 2025 PDF (852.74 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejvs.2025.416243.3067 | ||
| Authors | ||
| Asfand Yar Khan* 1; Aftab Shaukat2; Muhammad Muneeb1; Muhammad Kamal Shah1; Irfan Shaukat3; Muhammad Tahir Aleem4; Farhan Afzal5; Tauseef Ur Rehman6; Suliman Khan7; Zia Ud Din8; Konul Ahmadova9 | ||
| 1Faculty of Veterinary and Animal Sciences, Gomal University, Dera Ismail Khan, Pakistan | ||
| 2College of Veterinary Medicine, South China Agricultural University, Guangzhou, China | ||
| 3Department of Biochemistry, University of Narowal, Narowal, Pakistan | ||
| 4Department of Pharmacology, Shantou University Medical College, Shantou, China | ||
| 5Poultry Research Institute Shamas abad Muree Road Rawalpindi | ||
| 6Faculty of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Pakistan | ||
| 7Department of Veterinary Physiology and Biochemistry LUAWMS, Uthal, Baluchistan, Pakistan | ||
| 8CASVAB University of Balochistan Quetta Pakistan | ||
| 9Department of Life Sciences, Western Caspian University, Baku, Azerbaijan | ||
| Abstract | ||
| This study investigated the prevalence of haemoprotozoan infections in exotic cattle, their effects on Haematological parameters, and the comparative efficacy of different therapeutic agents. A total of 200 blood samples were collected from exotic cattle on private farms in Dera Ismail Khan, Pakistan, between April 13 and September 13, 2024. Samples were examined microscopically using Giemsa stain, and the haematological parameters [red blood cell count (RBCs), white blood cell count (WBCs), platelet counts, packed cell volume (PCV), and haemoglobin concentration (Hb) concentration] were determined with a veterinary haematology analyzer. Haemoprotozoan-positive cattle were divided into four groups: Group A (Anaplasma spp.), Group B (Anaplasma spp. + Babesia spp.), Group C (Babesia spp.), and Group D (Theileria spp.). Group A and B were treated with imidocarb dipropionate (2.5 mL/100 kg), Group C with diminazine aceturate (10 mL/300 kg), and Group D with buparvaquone (1 mL/20 kg). Overall prevalence of haemoprotozoan infection was 21.5%, including Anaplasmosis (7%), Babesiosis (5.5%), mixed infection of Anaplasma spp. + Babesia spp. (4.5%), and Theileriosis (4.5%). Therapeutic trials indicated highest efficacy against Babesiosis (81.8%), followed by Theileriosis (77.7%), mixed infection (77.7%), and Anaplasmosis (71.4%). Haematological analysis showed significant post-treatment improvement in RBC counts in Groups A, C, and D at day 7. Additionally, the study evaluated tick infestation rates in relation to different flooring types to identify possible predisposing factors for haemoprotozoan infections. In conclusion, haemoprotozoan infections are prevalent in exotic cattle in Dera Ismail Khan, adversely affecting Haematological values. Imidocarb dipropionate, diminazine aceturate, and buparvaquone demonstrated effective therapeutic efficacy under local field conditions and can be recommended for effective management of these infections. | ||
| Keywords | ||
| Haemoprotozoan infections; Anaplasmosis; Babesiosis; Theileriosis; Chemotherapy; Haematological parameters; Exotic cattle | ||
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