Investigating the Biochemical Links in Hypertensive Chronic Kidney Disease | ||
| Aswan Science and Technology Bulletin | ||
| Articles in Press, Accepted Manuscript, Available Online from 12 November 2025 PDF (463.07 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/astb.2025.404449.1027 | ||
| Authors | ||
| Eman Eid Abdelatey* 1; Mohamed Ali Khalil1; Mie Afify2; Mohamed Diaa El-Din Abdelmaksoud2; Samir Azazy3; Weaam gouda2 | ||
| 1chemistry department, faculty of science, Aswan university, Egypt. | ||
| 2Biochemistry Department, Biotechnology Research Institute, National Research Centre, Egypt. | ||
| 3Surgical Urology Department, faculty of medicine, Ain shams university, Egypt | ||
| Abstract | ||
| Abstract Chronic kidney disease (CKD) and hypertension are two medical conditions that are related to each other. This study aims to evaluate the relationship between CKD associated with hypertension and biochemical parameters such as kidney function (urea, creatinine, glomerular filtration rate) and blood electrolytes (sodium, potassium, calcium) and random blood sugar levels. The participants in this research were suffering from CKD and Hypertension. Creatinine, urea, and random blood sugar levels were measured using colorimetric methods, and sodium, potassium, and calcium levels were measured using the Ion-Selective Electrode (ISE) method. The glomerular filtration rate (GFR) was also estimated through the MDRD formula. Our study revealed significant associations between chronic kidney disease-associated hypertension and various biochemical parameters, including kidney function indicators (urea, creatinine, glomerular filtration rate), electrolytes (sodium, potassium) and hemoglobin levels. According to the findings, hypertensive chronic kidney disease significantly affects kidney function. Controlling blood pressure and keeping a close eye on kidney function are advised to prevent the advancement of chronic kidney disease and enhance patient outcomes. | ||
| Keywords | ||
| Chronic kidney disease (CKD); Kidney functions; estimated Glomerular filtration rate(eGFR); Clinical parameters; Hypertension | ||
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