Update of the Diagnosis of Zoonotic Hydatidosis Disease in Human
Mobarak, A., Abd-Ellah, O., Abuelwafa, E., Barakat, A. (2025). Update of the Diagnosis of Zoonotic Hydatidosis Disease in Human. EKB Journal Management System, (), 1-7. doi: 10.21608/ejvs.2025.425071.3133
Asmaa Hamdy Mobarak; Osama Hussein Abd-Ellah; Eman Abdelazeem Abuelwafa; Ashraf Mohamed Barakat. "Update of the Diagnosis of Zoonotic Hydatidosis Disease in Human". EKB Journal Management System, , , 2025, 1-7. doi: 10.21608/ejvs.2025.425071.3133
Mobarak, A., Abd-Ellah, O., Abuelwafa, E., Barakat, A. (2025). 'Update of the Diagnosis of Zoonotic Hydatidosis Disease in Human', EKB Journal Management System, (), pp. 1-7. doi: 10.21608/ejvs.2025.425071.3133
Mobarak, A., Abd-Ellah, O., Abuelwafa, E., Barakat, A. Update of the Diagnosis of Zoonotic Hydatidosis Disease in Human. EKB Journal Management System, 2025; (): 1-7. doi: 10.21608/ejvs.2025.425071.3133

Update of the Diagnosis of Zoonotic Hydatidosis Disease in Human

Egyptian Journal of Veterinary Sciences
Articles in Press, Corrected Proof, Available Online from 12 November 2025    PDF (748.81 K)
Document Type: Review Artical
DOI: 10.21608/ejvs.2025.425071.3133
Authors
Asmaa Hamdy Mobarak1; Osama Hussein Abd-Ellah2; Eman Abdelazeem Abuelwafa1; Ashraf Mohamed Barakat* 3
1Department of Medical Parasitology, Qena Faculty of Medicine, South Valley University
2Department of Medical Parasitology, Qena Faculty of Medicine, South Valley University.
3Department of Zoonotic Diseases, Veterinary Research Institute, National Research Centre, Cairo, Egypt.
Abstract
Hydatidosis is a zoonosis, a disease transmissible from animals to humans, caused by the parasite Echinococcus. Echinococcus granulosus, the cause of cystic echinococcosis (CE), is transmitted from carnivores to intermediate hosts, including livestock and humans. The parasite has multiple genotypes, with the sheep strain (G1) responsible for most human infections. Its life cycle involves ingestion of eggs that hatch into larvae forming hydatid cysts in organs, predominantly liver (75%) and lungs (15%). These cysts, composed of pericyst, laminated, and germinal layers, may contain brood capsules, hydatid sand, and cyst fluid. CE is globally prevalent, with significant health and economic impact, especially in endemic regions. Diagnosis combines serology, molecular PCR techniques, genotyping, and imaging (US, CT, MRI). Advanced methods use nanotechnology to enhance detection. Treatment includes surgery, chemotherapy (albendazole, mebendazole), and PAIR, with PAIR showing superior outcomes in selected cases. Long-term imaging follow-up is essential. Prevention relies on dog deworming, safe slaughter practices, public health measures, and vaccination in animals.
Keywords
Echinococcus granulosus; Cystic echinococcosis; Genotyping; Phylogenetic analysis
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