Neurological Complications of Covid-19 in Patients Presented to Zagazig University Hospital: A Cross- Sectional Study | ||
| Zagazig University Medical Journal | ||
| Articles in Press, Accepted Manuscript, Available Online from 14 November 2025 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2025.428705.4228 | ||
| Authors | ||
| Ahmed M. Tawfik* 1; Hossam Mohamed Refat2; Huda E. M. Said3; Omneia Ashraf shaheen4; Mohammad Abdelhay Rashid5 | ||
| 1Lecturer of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Zagazig University | ||
| 2Lecturer of Neurology, Faculty of Medicine, Zagazig University | ||
| 3Lecturer of Clinical pathology, Faculty of Medicine, Zagazig University | ||
| 4Lecturer of Chest Diseases, Faculty of Medicine, Zagazig University | ||
| 5Intensive Care Unit Resident at Al Qenayat Central Hospital, Egypt | ||
| Abstract | ||
| Background: COVID-19 has a variety of clinical presentations, from mild respiratory symptoms to serious bodily complications. Aim: In this study we aim to detect neurological complications to improve outcome in COVID-19 cases Methods: A retrospective study was performed by reviewing the clinical records of 98 cases with COVID-19. All relevant demographic data, comorbidities, symptoms, and the need for respiratory support were recorded. Descriptive analysis of delirium prevalence and clinical pattern - hypoactive and hyperactive types - was also performed. Results: Delirium was established in 50% of patients. Hypoactive delirium (40.8%) relates to aging and frailty, whereas hyperactive delirium (59.2%) relates to systemic inflammation and metabolic derangements. Males are 58.2% of study subjects. Coexisting diseases among comorbid patients included diabetes (43.9%) and hypertension (51.0%). Respiratory support was required in 99% of patients (25.5% by face mask, 27.6% by non-rebreather mask, 31.6% by continuous positive airway pressure [CPAP], and 14.3% by invasive mechanical ventilation [MV]), Neurological complications were detected in 79.6% of cases, with delirium identified in 50%. Conclusion: The findings highlight delirium- hypoactive and hyperactive types in terms of prevalence as a relevant feature in COVID-19. Comorbidities and the need for respiratory support drastically increase the gravity of the disease. Early identification and appropriate treatment of delirium, as well as its related complications, are key to improving clinical outcomes. | ||
| Keywords | ||
| COVID-19; Delirium; Neurological complication; Headache | ||
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